OBGYN Flashcards
By week _____ , fetal heart can be seen beating, BHcG: 1500, Yolk sac visualized
5 weeks
_____ is given to baby for HIV + mother on heart following delivery
Zidovudine
_______ cause increases in AFP during early trimester villious/chorio/CF-DNA sampling
Neural tube defect, ventral wall defect
increased AFP, + acetylcholinesterase a sign of _____ during early trimester screening
neural tube defect
decreased AFP + estriol, increased inhibin and HcG sign of ____ during early trimester screening
Downs Syndrome
Decreased AFP, Estriol, Inhibin, HcG is a sign of _____ during early trimester screening
Edwards Syndrome (Trisomy 18) : small head, jaw, overlapping clenched fingers
Gestational Diabetes Screening (Not Just A1C) : Glucose Load Test
Screen: 50 gram load, abnormal if glucose >_____
Definitive: 100 gram load, time series of glucose measurements
Fasting: ____
1 Hour: 180
2hr: ____
3hr: 140
130
95
155
When to give an RH(-) mother Rhogam for a child that’s RH (+)
1) ________, regardless
2) Post Delivery (peri window = 72hrs)
3) Miscarriage/Abortion
4) Instrumentation: Amniocentesis , CVS
5) _________
28 weeks
heavy vaginal bleeding
When is trimester screening recommended, ______ age
35+
Minimum age for amniocentesis _____
15 weeks (3+ months)
Thirst Trimester Bleeding Actions
1) ______
2) Pelvic Exam
Abdominal/Pelvic US, if placental previa you don’t want to rupture the placenta unknowingly
_______ cause of 3rd trimester bleeding usually results in painless bleeding, risk includes advanced age, multiple gestations, smoking/cocaine
Placenta Previa
Delivery Bleeding
1) ______ caused by placenta cemented to uterus
2) ______ caused by vilamentous cord insertion, umbilical vessels migrating across cervix
1) Placenta Accreta
Accreta: On top of myometrium
Increta : Into myometrium
Percreta : Through serosa, even into the bladder
2) Vasa Previa : Emergency C section, since fetus is affected and will become bradycardic
If GBS (+), plan for C section, Abx needed for GBS: Y/N
N
Indications for GBS treatment
1) GBS (+) Screen
2) _______
3) Maternal Fever
4) Pre-term labor
Extended membrane rupture >18hrs
Maternal toxoplasmosis treated with ______
Bacterim
limb hypoplasia, microcephaly, cataract, chorioretinitis, skin lesions in newborn, caused by ________
Varicella
Treatment for Varicella (+) pregnant mother
1) Acyclovir
2) _____
3) Vaccine
IgG immunoglobin
Treatment for neonate, if varicella suspected from maternal screen
1) ____
2) Acyclovir
IgG Immunoglobin
deafness, PDA, cataract, retardation, hepato-splenomegaly, thrombocytopenia –> blueberry muffin rash in newborn ________
Rubella
Two TORCH notorious for neonatal deafness
1) Rubella
2) ____
CMV
microcephaly, jaundice, periventricular calcifications, chorioretinitis, hepatosplenomegaly in newborn_______
CMV
Mother testing (+) for CMV, treat with ______
IgG + Gancicyclovir
_____ is a safe ART for HIV in mother and neonates. Neonates treated for ______ weeks
Zidovudine
6
anemia, thrombocytopenia, hepatosplenomegaly, swollen placenta, hydrops fetalis –> hutchison teeth, mulberry molars, saddle nose, sabre shins, deafness (bone effects are late infection______ neonatal infection
Syphillis
HepB post exposure prophylaxis_____
Vaccine + IgG
IUGR (Growth<10th percentile on US)
Symmetric [Systemic : Infection, Body Structure]
Aneuploidy
TORCH
Structural : NTD, congenital heart, ventral wall defect
Dx: karyotype, infection screen
Asymmetric [Fetal Connection Structures, Maternal]
Fetus : placental abruption, twin-twin steal, vilamentous cord insertion, infarction of placenta
Maternal : HTN, malnutrition, vasculitis, drugs, fetal hypoxia
Dx; Serial sono-grams , nonstress test
_____ is an evolution of preeclampsia, all warning sign s present (end organ damage: transaminases, RUQ, thrombocytopenia, AKI, pulm edema, headache/vision changes)
HELLP
Tx: Deliver (past 34 weeks) immediately
Preclampsia with seizure____
Eclampsia
BP control for preclampsia
BP>160/110 , over control leads to lower perfusion to the fetus. Hydralazine/Labetolol
Suspected PE in pregnant female, ______ test
VQ scan, avoid CT due to radiation exposure
VSD that becomes R–> L shunt is called_____ syndrome
Eisenmenger syndrome
PE during pregnancy = ____ chance of underlying clotting disorder, therefore send anti-coag workup
50%
Common thrombophilia Antithrombin 3 Factor 5 Leiden Prothrombin Antiphospholipid Hyperhomocystein
PE during pregnancy = ____ chance of underlying clotting disorder, therefore send anti-coag workup
50%
Common thrombophilia Antithrombin 3 Factor 5 Leiden Prothrombin Antiphospholipid Hyperhomocystein
How much to dose adjust up for hypothyroid ______ in pregnant
25%
___ is indicated for preeclampsia prophylaxis among gestational diabetes patients
Aspirin
_____ is ok to use during pregnancy, but not breast feeding
Metformin, Glyburide
_____ is a fetal syndrome associated with diabetes, not macrosomia
Caudal regression syndrome
- Non development of sacrum, lower extremities
Target LS ratio for fetal lung maturity
2.5
nocturnal pruiritis on palms/soles, increase Tbili, dark urine among pregnant women is caused by ________
Intrahepatic Cholestasis of Pregnancy
Tx: Ursodeoxycholic acid
______ can occur in pregnant women, in which RUQ pain, ascites, jaundice, encephalopathy
Tx: _____
Fatty Liver of Pregnancy
Tx: Deliver as soon as possible, as appropriate
Tx for pyelonephritis in a pregnant woman_____
Ceftrioxone + Gentamycin , can’t use quinolone
halperidol, risperidone, SSRI, metoclopramide are groups of medications famous for causing _____ side effect
Galactorrhea
- Medication gallactorhea is typically bilateral, unilateral needs to be investigated
Treatment for fibrocystic breast changes_____
OCP
Women>35 with first degree relative history, may do prophylaxis with _____ for breast cancer
Anastrazole
DCIS Treatment
1) Lumpectomy
2) Adjuvant radiation
3) _______ for 5 years
Tamoxifen/Anastrazole
Indication for Masectomy instead of Lumpectomy
1) Size > _____
2) 2+ quadrants
3) + margins
5cm
Indication for Adjuvant Chemo for ductal breast carcinoma
1) Size>____
2) Lymph node (+)
1cm
Premenarchial Bleeding Lesions
1) _______
2) Pitutiary/Ovarian tumor producing estrogen
Dx: _____
Sarcoma Botyroides
Pelvic exam under anesthesia