OB Exam 1 Flashcards
What is the goal to genetic testing?
Identify risk
Your client wants to know how to tell if she is ovulating. Select all that apply:
A. Cervical mucus is thick, sticky, and opaque white
B. Basal body temp drops slightly, then spikes 1/2 a degree
C.menstural period is just starting, spotting
D.positive test for spike in LH
E. Levels of progesterone are decreasing
B,D
How long is an egg fertile for after ovulation?
12-24 hours
Where does fertilization occur?
Outer 1/3 of fallopian tube
how long does it take a zygote to travel to the uterus?
3-4 days
Morula
“Solid ball of cells”, gives rise to blastocyst= embryoblast(embryo) and trophoblast (placenta)
when does blastocyst implant into endometrium?
6-10 days after conception, usually into fundus
How long does the sperm remain viable in female reproductive tract?
At least 2-3 days
(possibly 3-5 days)
Which is counted as the first day of the menstrual cycle?
A. First day of bleeding during menses
B. Day of ovulation
C. Last day of bleeding during menses
D. Day before the menstrual bleeding starts
The first day of bleeding during menses
How long after intercourse could she get pregnant?
Sperm can reach site of fertilization in 5 minutes; conception likely up to a week after intercourse (sperm viable 3-5 days in female tract) and implantation (pregnancy) 2-3 weeks after
How long after ovulation could she get pregnant?
five days before ovulation, the day of ovulation, and one day after ovulation (sperm can live 3-5 days, ova fertile for 24 hours)
What is included in genetic counseling?
Information, education, and support
How many pregnancy genetic tests are there?
4
What is the first (earliest) genetic test that can be done in pregnancy?
CVS (chorionic villus sampling)
When can a CVS be done?
10-13 weeks
What is a CVS?
Chorionic villus sampling: tissue sample of the placenta
Indicated: risk for giving brith to neonate with genetic chromosomal abnormality (cannot determine spina bidifida or anencephaly)
Full bladder necessary for testing
What are the four pregnancy genetic tests?
Chorionic villus sampling, amniocentesis, alpha-fetoprotein, and level 2 ultrasound/targeted ultrasound
What is an amniocentesis?
Sample of amniotic fluid, empty bladder needed (avoid puncture)
When is an amniocentesis done?
15-20 weeks
What is an AFP test?
Alpha-fetoprotein test of maternal blood
When is an alpha-fetoprotein test done?
15-18 weeks
When is a level 2 ultrasound (targeted ultrasound) done?
After 18 weeks
What is a level 2/targeted ultrasound?
Complete scan of fetal anatomy
What area is more likely to be damaged during childbirth?
Perineum
What is the pear shaped organ?
Uterus
Organ made of hollow smooth muscle with constant rhythmic contractions, lined with cells responsive to hormones
Uterus
What is a gynecoid pelvis?
Perfect shape and angle that is most optimum condition for vaginal delivery
Presumptive signs of pregnancy
Amenorrhea, fatigue, N/V, urinary frequency, breast changes, quickening(Could be gas), uterine enlargement
What is quickening?
The mother feels the movement of the baby
Probable signs of pregnancy
Abd enlargement, Hegar’s sign, Chadwick’s sign, Goodell’s sign, Braxton Hicks contractions, positive pregnancy test, fetal outline felt by examiner(could be tumor, anatomy)
Confirmation of pregnancy: positive indicators
Auscultation FHR, fetal movements felt by examiner, visualization of embryo/fetus by ultrasound
Risk for CVS
Spontaneous abortion, risk for fetal limb loss (greatest risk=prior to 9 weeks), miscarriage, chorioamnionitis and rupture of membranes
Risk for amniocentesis
Amniotic fluid emboli, maternal/fetal hemorrhage,maternal/fetal infection ,inadvertent fetal damage/anomalies involving limbs, fetal death, inadvertent maternal intestinal/bladder damage,miscarriage/preterm labor,premature rupture of membranes,leakage of amniotic fluid
key points for amniocentesis
Empty bladder prior to procedure
Baseline vitals and FHR prior to
Monitor vs, FHR, uterine contractions throughout and 30 min following
Client rest for 30 min
Administer Rho(D) immune globulin to client if they are Rh-Negative
Risk for AFP test
Low AFP= Down syndrome
High AFP= neural tube defects
Placenta previa vs placental abruption
Placenta implants in lower segment of uterus covering cervical opening vs premature separation of placenta from uterus
Presentation for placenta previa
Painless, bright red vaginal bleeding during 2nd and 3rd trimester; higher than expected fundal height; fetus may be breech, oblique, or transverse
Risk factors for placenta previa
Previous previa, uterine scarring, advanced maternal age (>35), multi fetal pregnancy, multiple gestations, smoking
Presentation for placental abruption
Partial or complete detachment of placenta after 20 weeks; sudden onset of intense localized uterine pain, dark red vaginal bleeding, “board-like” with palpation, contractions with hypertonicity, fetal distress
Risk factors for abruptio placentae
Maternal HTN, trauma (MVA=biggest), cocaine(substance abuse), history of abruption, smoking, PROM(premature rupture of membranes), Multifetal pregnancy
Tx plans for placenta previa
Assess bleeding, leakage, or contractions; fundal height; NO vaginal exams; prepare to give IVF, blood products, betamethasone, prepare for c section, bed rest, nothing inserted into vagina
Tx plans for placental abruption
Palpate uterus for tenderness, serial monitoring for fundal height, FHR monitoring, emotional support, Delivery is only management for abruption
Ectopic pregnancy
Abnormal implantation of ovum outside of uterine cavity; second most frequent cause of bleeding in early pregnancy
expected findings for ectopic pregnancy
Unilateral stabbing pain, tenderness in lower quadrant, scant dark red or brown vaginal spotting
If ruptured, bleeding is red
Tx for ectopic pregnancy-ruptured
Methotrexate (dissolves pregnancy) and laparoscopic salpingectomy
Tx for ectopic pregnancy-non ruptured
Methotrexate and salpingostomy to salvage fallopian tube
Hegar’s sign
softening and compressibility of lower uterus
Chadwick’s sign
Deepened violet-bluish color of cervix and vaginal mucosa
Goodell’s sign
Softening of cervical tip
Non-stress test
Monitors FHR in response to fetal movement; client pushes button when she feels fetal movement
Reactive vs non reactive
Positive non-stress test
Reactive= two or more accelerations within a 20 min period
Negative nonstress test
Non reactive= fewer than two accelerations in 40 min period
Contraction stress test
Nipple stimulated and oxytocin stimulated
(Contractions must be started)
Analysis of FHR response to contractions, determines how fetus will tolerate labor stress
What should be avoided with contraction stress test?
Hyperstimulation of uterus (contraction longer than 90 seconds or five or more contractions in 10 min)
When is oxytocin stimulated contraction stress test used?
If nipple stimulation doesnt work. More difficult to stop… can lead to preterm labor
Contraindications for oxytocin-stimulated contraction stress test
Placenta previa, vasa previa, preterm labor, multiple gestations,previous classic incision from c section, reduced cervical competence(insufficiency)
Quad marker screening
Blood test to provide info about likelihood of fetal birth defects- DOES NOT DX
Can be used instead of maternal AFP blood level, yields more reliable results
What does quad marker screening test for?
Human chorionic gonadotropin (hCG), alpha-fetoprotein (AFP), estriol, inhibin A
Low levels of AFP indicate
Risk for Down syndrome
high levels of AFP indicate
Risk for Neural tube defects
Higher than expected levels of hCG and inhibin A indicate…
Risk for Down syndrome
lower levels than expected for estriol can indicate…
Risk for Down syndrome
Positive and negative contraction stress test
reactive and nonreactive
When is a BPP ordered?
Non reactive stress test, suspected oligohydramnios or polyhydramnios, suspected fetal hypoxemia or hypoxia
What is a BPP?
Biophysical profile ; uses ultrasound to visualize physical and physiological characteristics of fetus, observes for fetal response to stimuli, combo of FHR and fetal ultrasound monitoring
What is the BPP assessing?
FHR, fetal breathing, body movements, fetal tone (flexed?), amount of amniotic fluid
BPP scoring
8-10=normal, low risk of chronic fetal asphyxia
4-6= abnormal, suspect chronic fetal asphyxia
Less than 4= strongly suspect chronic fetal asphyxia—>possible delivery
each category=0-2
If quad marker screening tool shows abnormalities…
Diagnostic tools (depending on gestation) needed for Dx (amino or CVS)
Maternal alpha-fetoprotein results
High levels indicate neural tube defect/open abdominal defect
Low levels can indicate Down syndrome
ONLY A SCREENING TOOL
Stages of fetal development
Two stages: embryonic and fetal
embryonic stage
Day 15-8 weeks gestation
Most critical time in development of organ systems
Most vulnerable to malformations caused by environmental teratogens
what stage is the most critical time in development of organ systems?
Embryonic: All organ systems are present by end of 8 weeks
What stage is most vulnerable to malformations caused by environmental teratogens?
Embryonic
During embryonic stage, the amniotic fluid…
Cushions against impact to maternal abdomen
Maintains stable temp
Allows symmetric development(neutral position for fetus to develop properly, defies gravity)
Prevents membranes from adhering to fetal parts
Allows room and buoyancy for fetal movement
Hormones produced by placenta
Chorionic gonadotropin
Prolactin
Estrogen
Progesterone
Relaxin
When is quickening felt?
Subsequent=18-19 weeks
First-time moms= 20-22 weeks
Monozygotic twins
“Identical”
1ovum/1sperm->2 babies