OB Flashcards
placenta abruption symptom triad
- uterine contraction
- hypertonic uterine
- painful vaginal bleeding/ constant abdo or back pain
- (non-reassuring FHR)
DDx of vaginal bleeding in 2nd to 3rd trimester
non-painful vaginal bleeding
- placenta previa (20% of bleeds)
- vasa previa
- bloody show (PPROM)
“Painful” vaginal bleeding
- placenta abruption (40% of bleeds)
- uterine rupture
placenta previa symptoms
- painless vaginal bleeding
- fetal distress
placenta abruption risk factors
- PPROM
- Multiparity
- previous abruption
- HTN
- T2DM
- smoking (not in otool’s book)
- thrombophilia (Fibrinogen)
- fibroid
- drugs
- age < 20 or > 35 y/o (not in FM note)
- trauma
placenta previa risk factors
- previous placenta previa
- previous c/s
- multiparity
- multiple gestations
- smoker
- fibroid
risk factors of vasa previa
- low lying placenta
- multi-lobed placenta
- IVF
< Placenta previa>
definition
placenta attached to the lower segment of uterus < 2cm from os
What are the symptoms of early show?
- effacement
- dilation of cervix
- mucous plug passes
< placenta abruption>
What are the work-ups of placenta abruption?
- u/s with decreased sensitivity (20% with no vaginal bleeding)
- Kleihauser-Betke (fetal cells in mat blood)
- fibrinogen
- CBC, BUN/CRE, Rh and ABO type and cross
- PT/aPTT (increased risk of DIC)
Vasa previa work-up investigation
and Management
- Apt test
(positive= fetal blood in vaginal blood; neg: only maternal blood) - Wright test/ stain
Management: urgent c/s
management
- OB emergency
- ABC, IVF, monitor for DIC
- Pre-term - admit + monitor
- term + stable: induced VD
- unstable: c/s
placenta previa management
- u/s to confirm type: accreta vs. increta vs. percreta
- c-section (try to wait until 37 wks)
- bed rest, Celestone (for lung maturation)
- serial CBC, fetal monitoring
DDx of vaginal bleeding in 1st to 2nd trimester
- Non-obstetrical ddx
Non-obstetrical ddx:
- trauma (post-coital, partner violence, sexual assault)
- genital lesions (cervical polyps, neoplasm)
- cervicitis/ vaginitis
- hemorrhagic cyst
- perineal lesions
- vulvar varicosities
- rectal bleeding (lower GI)
- UTI/ hematuria
DDx of vaginal bleeding in 1st to 2nd trimester
- Obstetrical ddx
- 20% of pregnancies will have bleeding before 20 w GA
- physiological bleeding - spotting, implantation bleed
- abnormal pregnancy (ectopic, molar)
- abortion
Investigation of vaginal bleeding in 1st to 2nd trimester
- CBC + blood type
- beta-hCG
- pap + swabs
- transvaginal us
Which types of abortion has cervix still closed?
How are they managed?
- threatened abortion (<5%): mild bleed +/- cramps
> u/s - viable fetus? FHR? ectopic? - missed abortion: fetal pole > 6mm w/ no FHR (fetal demise) - NO blood, no uterine activity
> D+C +/- Oxytocin 50% resolve in 2 wks - sepsis abortion (can be closed or open): spontaneous abortion complicated by uterine infection
> SIRS (temp<36 or>38, leuk<4 or >12, RR>20, HR>90)
> IV abx (gentamicin + clindamycin)
Def of recurrent/ habitual abortion
> or = 3 consecutive pregnancy losses
Def of spontaneous abortion
pregnancy loss < 20w GA
* 10% of known pregnancies will end in spontaneous abortion
Antiphospholipid syndrome (APS) diagnosis criteria
Clinical criteria (1) AND (2)
(1 ) vascular thrombosis: one or more clinical episodes of arterial, venous, or small-vessel thrombosis in any tissue or organ confirmed by findings from imaging studies, Doppler studies, or histopathology
(2) pregnancy morbidity
- One or more late-term (>10 weeks’ gestation) spontaneous abortions
- One or more premature births of a morphologically healthy neonate at or before 34 weeks’ gestation because of severe preeclampsia or eclampsia or severe placental insufficiency
- Three or more unexplained, consecutive, spontaneous abortions before 10 weeks’ gestation
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Laboratory criteria include any of the following:
- Medium to high levels of immunoglobulin G (IgG) or immunoglobulin M (IgM) anticardiolipin (aCL) Anti–beta-2 glycoprotein I
- Lupus anticoagulant on at least two occasions at least 12 weeks apart
absolute contraindication of medical abortion
- ectopic
- chronic adrenal failure
- inherited porphyria
- uncontrolled asthma
relative contraindication of medical abortion
- unconfirmed GA
- IUD
- concurrent systemic corticosteroid
- hemorrhagic disorder or concurrent anti-coagulation
Risks of medical/induced abortion
- bleeding
- cramping/pelvic pain
- GI symptoms (N/V/diarrhea)
- headache
- fever or chills
- pelvic/ lower genital infection
- mortality (0.3 per 100,000, most from infection or undiagnosed ectopic)