endocrine Flashcards

1
Q

Complications of obesity

A
  • Type 2 diabetes
  • Gallbladder disease
  • Nonalcoholic fatty liver disease
  • Gout

Obesity increases the risk of the following cancers:

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2
Q

Indication of pharmacological therapy for obesity

A
  • BMI ≥30 kg/m2 OR

- BMI ≥27 kg/m2 with obesity (adiposity) related complications

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3
Q

Pharmacological Therapy options for obesity

A

a. liraglutide
b. naltrexone/bupropion(in a combination tablet)
c. orlistat

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4
Q

indications for bariatric surgeries for obesity

A
  • BMI ≥40 kg/m² OR
  • BMI ≥35 - 40 kg/m² with an obesity (adiposity) related complication OR
  • BMI ≥30 kg/m² with poorly controlled type 2 diabetes
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5
Q

types of bariatric surgery for obesity

A

a. Sleeve gastrectomy
b. Roux-en-Y gastric bypass
c. Biliopancreatic diversion with/without duodenal switch

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6
Q

definition of obesity

A

Obesity is operationally defined as a BMI exceeding 30 kg/m2 and is subclassified into class 1 (30–34.9), class 2 (35–39.9) and class 3 (≥ 40)

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7
Q

what is the 5As Framework for Obesity Management in Adults

A
  1. Ask
  2. Assess
  3. Advice:
    Medical Nutrition Therapy (MNT) and Physical
  4. Activity
  5. Agree
  6. Assist
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8
Q

best iron supplement for adult and children

A

Adult: ferrous fumarate
children: ferrous sulfate

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9
Q

What are the thalassemia testing?

A
  • Anemia work-up
  • Iron studies
  • Hemoglobin electrophoresis
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10
Q

risk factors of Vitamin B12 deficiency

A
  • Gastric surgery (gastric parietal cells produce intrinsic factor)
  • strict vegan
  • breastfed children of #2
  • elderly
  • psychiatric
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11
Q

what are the diagnostic tests for pernicious anemia

A
  • Vitamin B12 level
  • when B12 low, check anti-intrinsic factor antibody
    if positive, confirm pernicious anemia
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12
Q

Management for anemia

A
  • transfusion if
    1) hemoglobin < 70 AND
    2) symptomatic

Find causes

  • reduced intake
  • loss: menstrual, GI bleeding
  • destruction: marathon runner

Investigation:

  • colonoscopy
  • urinalysis
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