O&G

Question 1

COCP absolute contraindications (UMEK 4)

Answer 1

• more than 35 years old and smoking more than 15 cigarettes/day
• migraine with aura
• history of thromboembolic disease or thrombogenic mutation
• history of stroke or ischaemic heart disease
• breast feeding < 6 weeks post-partum
• uncontrolled hypertension
• current breast cancer
• major surgery with prolonged immobilisation
• positive antiphospholipid antibodies (e.g. in SLE)

Question 2

COCP contraindications (UMEK 3)

Answer 2

• more than 35 years old and smoking less than 15 cigarettes/day
• BMI > 35 kg/m^2*
• family history of thromboembolic disease in first degree relatives < 45 years
• controlled hypertension
• immobility e.g. wheel chair use
• carrier of known gene mutations associated with breast cancer (e.g. BRCA1/BRCA2)
• current gallbladder disease

Question 3

Ovarian ca

Answer 3

5th most common

peak incidence 60 years

epithelial > serous

Risk: BRCA1 or 2, early menarche, late menopause, nulliparity

CA125

COCP protective