Diabetes Flashcards
1
Q
Sulfonylureas
A
- Gliclazide
- second line drug, SUR-1 receptor on beta cells
- bind to an ATP-dependent K+(KATP) channel
- increases pancreatic insulin secretion
Adverse effects:
- hypo
- weight gain
- hypoNa
- bone marrow suppresion
- hepatotoxicity
- peripheral neuropathy