Diabetes Flashcards

1
Q

Sulfonylureas

A
  • Gliclazide
  • second line drug, SUR-1 receptor on beta cells
  • bind to an ATP-dependent K+(KATP) channel
  • increases pancreatic insulin secretion

Adverse effects:
- hypo
- weight gain

  • hypoNa
  • bone marrow suppresion
  • hepatotoxicity
  • peripheral neuropathy
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