Nutrition, Metabolism, and Temperature Regulation Flashcards

1
Q

are the substances taken into the body that are used by the cells of the body to produce energy, to provide building blocks for new molecules, and to function in other chemical reactions.

A

Nutrition

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2
Q

is considered an important
component of our diet even though we cannot digest it. Instead, _____ adds to the bulk of feces, which stimulates normal motility of the large intestine.

A

Fiber

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3
Q

Nutrients are divided into six major classes:

A

(1) Carbohydrates
(2) Lipids
(3) Proteins
(4) Vitamins
(5) Minerals
(6) Water

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4
Q

are the major organic nutrients. They must be broken down by enzymes into their components during digestion before they can be absorbed by the small intestine.

A

Carbohydrates, Lipids, and Proteins

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5
Q

are required in fairly substantial quantities.

A

Carbohydrates, Lipids, Proteins, and Water

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6
Q

are required in only
small amounts.

A

Vitamins and Minerals

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7
Q

are absorbed by the digestive tract without being digested.

A

Vitamins, Minerals, and Water

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8
Q

are substances that must be ingested because the body cannot manufacture them at all or cannot manufacture adequate amounts of them.

A

Essential Nutrients

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9
Q

The essential nutrients include

A

certain amino acids and fatty acids,
most vitamins, minerals, water, and a few carbohydrates.

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10
Q

Other nutrients are necessary; if they are not part of the diet, they can be synthesized from the essential nutrients. Most of this synthesis takes place in the _____, which has a remarkable ability to transform and manufacture molecules.

A

Liver

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11
Q

is the amount of energy (heat) necessary to raise the temperature of 1 g of water 1°C.

A

calorie (cal)

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12
Q

is 1000 calories and is used to express the larger amounts of energy supplied by foods and released through metabolism.

A

Kilocalorie (kcal)

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13
Q

A kilocalorie is often called a

A

Calorie (with a capital C)

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14
Q

Most of the kilocalories supplied by food come from

A

Carbohydrates, Proteins, or Lipids (Fats)

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15
Q

For each gram of carbohydrate or protein the body metabolizes, about _____ of energy are released.

A

4 kcal

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16
Q

contain more energy per unit of weight than carbohydrates and proteins and yield about 9 kcal/g.

A

Fats

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17
Q

About 95% of the lipids in the human diet are

A

Triglycerides

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18
Q

Triglycerides, which are sometimes called _________, consist of three fatty acids attached to a glycerol molecule.

A

Triacylglycerols

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19
Q

Triglycerides are often referred to as (1) ____, which are solid at room temperature, or (2) ____, which are liquid at room temperature.

A

(1) Fats
(2) Oils

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20
Q

Fats and oils can be categorized as ________ or ________ depending on the types of bonds in the fatty acid.

A

Saturated, Unsaturated

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21
Q

have only single covalent bonds between the carbon atoms of their fatty acids.

A

Saturated fats and oils

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22
Q

have one or more double covalent bonds between the carbon atoms of their fatty acids

A

Unsaturated fats and oils

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23
Q

fats include olive and peanut oils

A

Monounsaturated

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24
Q

fats are in fish, safflower, sunflower, and corn oils.

A

Polyunsaturated

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25
Q

The “starting” point for determining the location of the double bonds is the _____ end of the fatty acid.

A

Omega (methyl)

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26
Q

The first double bond of an (1)_____ fatty acid starts three carbon atoms after the omega end; an (2)_____ fatty acid starts after six carbons; and an (3)______ fatty acid starts after nine carbons

A

(1) Omega-3
(2) Omega-6
(3) Omega-9

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27
Q

To saturate an unsaturated oil, the oil can be __________, which means that hydrogen gas is bubbled through the oil to produce a change in molecular shape that solidifies the oil.

A

Hydrogenated

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28
Q

The more _________ the product, the harder it becomes at room temperature

A

Saturated

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29
Q

These processed fats are usually referred to as

A

Trans fats

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30
Q

Unprocessed polyunsaturated fats are found mostly in the _______, which means the hydrogen atoms are on the same side of the carbon-carbon double bond in their fatty acids

A

Cis form

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31
Q

During hydrogenation, some of the hydrogen atoms are transferred to the opposite side of the double bond to make the _________, characterized by one hydrogen atom on one side of the double bond and another on the opposite side.

A

Trans form

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32
Q

raise the concentration of low-density lipoproteins and lower the concentration of high-density lipoproteins in the blood. These changes are associated with a greater risk for cardiovascular disease.

A

Trans fatty acids

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33
Q

The remaining 5% of lipids include _________ and _________, such as lecithin

A

Cholesterol and Phospholipids

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34
Q

is a steroid found in high concentrations in liver and egg yolks, but it is also present in whole milk, cheese, butter, and meats. ________ is not in plants.

A

Cholesterol

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35
Q

major components of plasma membranes, are found in a variety of foods, including egg yolks.

A

Phospholipids

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36
Q

Triglycerides are important sources of energy that can be used to produce

A

ATP

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37
Q

After a meal, excess triglycerides that are not immediately used are stored in ________ or the ________.

A

Adipose Tissue, Liver

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38
Q

In addition to storing energy, _________ surrounds and pads organs. _________ located under the skin is an insulator,
which prevents heat loss.

A

Adipose Tissue

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39
Q

Cholesterol is a component of the
plasma membrane, and it can be modified to form other useful molecules, such as ________ and ________.

A

Bile salts, steroid hormones

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40
Q

are necessary for lipid digestion and absorption.

A

Bile Salts

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41
Q

include the reproductive hormones estrogen, progesterone, and testosterone.

A

Steroid Hormones

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42
Q

which include prostaglandins and leukotrienes, are derived from fatty acids.

A

Eicosanoids

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43
Q

such as lecithin, are part of the plasma membrane and are used to construct the myelin sheath around the axons of neurons.

A

Phospholipids

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44
Q

is also found in bile and helps emulsify lipids.

A

Lecithin

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45
Q

Most of the carbohydrates humans ingest come from (1) _____. An exception is (2) _______, which is found in milk and other dairy products.

A

(1) Plants
(2) Lactose

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46
Q

are the most common monosaccharides in the diet.

A

Glucose and Fructose

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47
Q

Plants capture the energy in sunlight and use it to produce _______, which can be found in vegetables.

A

Glucose

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48
Q

are isomers of glucose

A

Fructose (fruit sugar) and galactose

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49
Q

When most of us think of sugar, we are probably thinking of the sugar you can buy in big bags in the grocery store. This is commonly referred to as

A

Table Sugar

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50
Q

Table sugar is actually the disaccharide

A

Sucrose

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51
Q

derived from germinating cereals, is composed of two glucose molecules.

A

Maltose (malt sugar)

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52
Q

consists of a glucose and a galactose molecule.

A

Lactose (milk sugar)

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53
Q

are polysaccharides, which consist
of many glucose molecules bound together to form long chains.

A

Complex Carbohydrates

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54
Q

Examples of common dietary polysaccharides include

A

Starch, Glycogen, and Cellulose.

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55
Q

is an energy-storage molecule found
primarily in plants (vegetables, fruits, and grains).

A

Starch

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56
Q

is an energy-storage molecule in animals and is located primarily in
muscle and in the liver.

A

Glycogen

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57
Q

forms plant cell walls.

A

Cellulose

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58
Q

During digestion, polysaccharides and disaccharides are split into monosaccharides, which are absorbed into the

A

Blood

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59
Q

Humans can digest starch and glycogen because our bodies produce _______ that break the bonds between the glucose molecules
of starch and glycogen.

A

Enzymes

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60
Q

Humans are unable to digest ________ because our bodies do not produce the enzymes that break the bonds between its glucose molecules.

A

Cellulose

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61
Q

As a consequence, the digestive tract is unable to absorb cellulose. Instead, cellulose provides _____, or “roughage,” thereby increasing the bulk of feces and making it easier to defecate.

A

Fiber

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62
Q

The _____ converts fructose, galactose, and other monosaccharides absorbed by the small intestine into glucose.

A

Liver

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63
Q

Glucose, whether absorbed from the digestive tract or synthesized in the liver, provides energy to produce _________ molecules.

A

Adenosine Triphosphate (ATP)

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64
Q

Because the _____ relies almost entirely on glucose for its energy, the body carefully regulates blood glucose levels.

A

Brain

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65
Q

Muscle and liver cells convert excess glucose into glycogen for

A

Storage

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66
Q

Cells can store only a limited amount of ________; therefore, any additional glucose is converted into lipids and
stored in adipose tissue.

A

Glycogen

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67
Q

can be rapidly converted back to glucose when energy is needed.

A

Glycogen

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68
Q

In addition to serving as a source of energy, sugars have other functions. They form part of

A

Deoxyribonucleic acid (DNA), Ribonucleic acid (RNA), and ATP molecules.

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69
Q

Sugars also combine with ________ to form glycoproteins, such as the glycoprotein receptor molecules on the outer surface of the plasma
membrane.

A

Proteins

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70
Q

According to the Dietary Guidelines Advisory Committee, the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates is _____ of total kilocalories

A

45–65%

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71
Q

Muscles are primarily protein, the use of proteins for energy can result in the breakdown of

A

Muscle Tissue

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72
Q

The extensive use of lipids for energy
can lead to

A

Acidosis

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73
Q

are recommended in the diet because
many starchy foods contain other valuable nutrients, such as vitamins and minerals.

A

Complex Carbohydrates

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74
Q

Foods primarily composed of ________, such as soft drinks and candy, are rich in carbohydrates but have few other nutrients.

A

Simple Sugars

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75
Q

A typical soft drink is mostly _______, containing 9 teaspoons of sugar per 12 oz can. Consuming these kinds of foods in excess usually results in
obesity and tooth decay.

A

Sucrose

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76
Q

The AMDR for lipids is _____ for adults

A

20–35%

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77
Q

The AMDR for lipids is _____ for children and adolescents 4 to 18 years of age

A

25–35%

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78
Q

The AMDR for lipids is _____ for children 2 to 3 years of age.

A

30–35%

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79
Q

Saturated fats should amount to no more than ___ of total kilocalories or be as low as possible.

A

10%

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80
Q

Most dietary fat should come from sources of

A

Polyunsaturated and monounsaturated fats

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81
Q

Essential fatty acids are used to synthesize ________ that affect blood clotting.

A

Prostaglandins

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82
Q

can be converted to arachidonic acid, an omega-6 fatty acid used to produce thromboxanes, which increase blood clotting.

A

Linoleic acid

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83
Q

can be converted to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), omega-3 fatty acids that can be used to synthesize prostaglandins, which decrease blood clotting.

A

Alpha- linolenic acid

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84
Q

People who eat foods rich in EPA and DHA, such as herring, salmon, tuna, and sardines, increase the synthesis of _________ from EPA and DHA.

A

Prostaglandins

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85
Q

Those who eat these fish two or more times per week have a lower risk for heart attack than those who do not, possibly because of reduced blood clotting.

A

Herring, Salmon, Tuna, and Sardines

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86
Q

EPA and DHA are also known
to reduce blood _______ levels.

A

Triglyceride

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87
Q

People who do not like to eat fish can take _______ supplements as a source of EPA and DHA.

A

Fish oil

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88
Q

is a source of alpha-linolenic acid, from which EPA and DHA can be synthesized.

A

Flaxseed

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89
Q

Most of the ________ consumed in the diet is broken down in the digestive tract.

A

Lecithin

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90
Q

The _____ can manufacture all the lecithin necessary to meet the body’s needs, so taking lecithin supplements is
not necessary.

A

Liver

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91
Q

The essential fatty acids in the human diet include

A

Alpha-linolenic acid and linoleic acid

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92
Q

These fatty acids must be ingested because humans lack the enzymes necessary to synthesize them.

A

Alpha-linolenic acid and linoleic acid

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93
Q

are good sources of alpha-linolenic and linoleic acids.

A

Seeds, nuts, and legumes

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94
Q

(1) ________ is in the
green leaves of plants, and (2) _______ is in grains.

A

(1) Alpha-linolenic acid
(2) Linoleic acid

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95
Q

are chains of amino acids.

A

Proteins

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96
Q

Proteins in the body are constructed of
20 kinds of amino acids, which are divided into two groups:

A

Essential and nonessential

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97
Q

The body cannot synthesize ________, so they must be obtained in the diet.

A

Essential amino acids

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98
Q

The nine essential amino acids are

A
  1. Histidine
  2. Isoleucine,
  3. Leucine
  4. Lysine
  5. Methionine
  6. Phenylalanine
  7. Threonine
  8. Tryptophan
  9. Valine
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99
Q

which are necessary to construct our proteins, do not necessarily need to be ingested because they can be synthesized from essential amino acids.

A

Nonessential amino acids

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100
Q

is a food that contains adequate amounts of all nine essential amino acids

A

Complete protein

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101
Q

Examples of complete protein foods are

A

Meat, fish, poultry, milk, cheese, and eggs

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102
Q

Examples of incomplete protein foods are

A

Leafy green vegetables, grains, and legumes (peas and beans)

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103
Q

If two incomplete proteins, such as rice and beans, are ingested together, the amino acid composition of each complements the other, and a
_________ is created.

A

Complete protein

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104
Q

provides structural strength in connective tissue, as does keratin in the skin.

A

Collagen

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105
Q

The interactions of ______ and
______ make muscle contraction possible.

A

Actin, Myosin

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106
Q

regulate the rate of chemical reactions

A

Enzymes

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107
Q

hormones regulate many physiological processes

A

Protein

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108
Q

in the blood prevent changes in pH (buffers), promote blood clotting (coagulation factors), and transport oxygen and carbon dioxide (hemoglobin).

A

Proteins

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109
Q

move materials across plasma membranes, and other proteins in the plasma membrane function as receptor molecules.

A

Transport proteins

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110
Q

are part of the immune system response that protects against microorganisms and other foreign substances.

A

Antibodies, lymphokines, and complement

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111
Q

The body also uses proteins for

A

Energy

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112
Q

As an energy source, proteins yield the same amount of kilocalories as

A

Carbohydrates

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113
Q

If excess proteins are ingested, the energy in the proteins can be stored by converting their _________ into glycogen or lipids.

A

Amino acids

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114
Q

The AMDR for protein is ____ of total kilocalories.

A

10–35%

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115
Q

The _________ of proteins contain nitrogen, so saying that a person is in nitrogen balance means that the nitrogen content of ingested protein is equal to the nitrogen excreted in urine and feces.

A

Amino acids

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116
Q

A starving person is in ______ nitrogen balance because the nitrogen gained in the diet is less than that lost by excretion. In other words, when proteins are broken down for energy, more nitrogen is lost than is replaced in the diet.

A

Negative

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117
Q

A growing child or a healthy pregnant woman is in _______ nitrogen
balance because more nitrogen is going into the body to produce
new tissues than is lost by excretion.

A

Positive

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118
Q

are organic molecules that exist in very small quantities in food. These molecules are essential to normal metabolism

A

Vitamins

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119
Q

cannot be produced by the body and must be obtained through the diet.

A

Essential vitamins

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120
Q

The absence of an essential vitamin in
the diet can result in a

A

Deficiency disease

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121
Q

A few vitamins, such as ________, are produced by intestinal bacteria, and a few others can be formed by the body
from substances called provitamins.

A

Vitamin K

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122
Q

is a part of a vitamin that the body can convert into a functional vitamin.

A

Provitamin

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123
Q

is a provitamin that the body can form into vitamin A.

A

Beta carotene

124
Q

The other provitamins are 7-dehydrocholesterol, which can be converted to (1) _______, and
tryptophan, which can be converted to (2) _______.

A

(1) Vitamin D
(2) Niacin

125
Q

Rather than breaking down vitamins by ________, the body uses them in their original or slightly modified forms.

A

Catabolism

126
Q

If the chemical structure of a vitamin is destroyed, its function is usually

A

Lost

127
Q

The chemical structure of many vitamins is destroyed by heat, as when food is

A

Overcooked

128
Q

Many vitamins function as ________, which combine with enzymes to make
the enzymes functional.

A

Coenzymes

129
Q

Without enzymes and their coenzymes, many chemical reactions would occur _____ to support good health and life.

A

Too slowly

130
Q

Vitamins B2 and B3, biotin, and pantothenic acid are critical for some of the chemical reactions involved in producing

A

ATP

131
Q

Folate and vitamin B12 are required for ________ synthesis.

A

Nucleic acid

132
Q

Vitamins A, B1, B6, B12, C, and
D are necessary for

A

Growth

133
Q

Vitamin B1

A

Thiamine

134
Q

Vitamin B2

A

Riboflavin

135
Q

Vitamin B3

A

Niacin

136
Q

Vitamin B5

A

Pantothenic acid

137
Q

Vitamin B6

A

Pyridoxine

138
Q

Vitamin B7

A

Biotin

139
Q

Vitamin B9

A

Folate

140
Q

Vitamin B12

A

Cobalamin

141
Q

Vitamin C

A

Ascorbic acid

142
Q

Vitamin A

A

Retinol

143
Q

Vitamin D

A

Calciferol

144
Q

Vitamin E

A

Tocopherol

145
Q

Vitamin K

A

Phylloquinone

146
Q

is necessary for the synthesis of proteins involved in blood clotting.

A

Vitamin K

147
Q

vitamins, such as vitamins A, D, E, and K, dissolve in lipids and are absorbed from the intestine along with lipids. Some of them can be stored in the body for a long time. Because they can be stored, these vitamins can accumulate in the body to the point of toxicity.

A

Fat-soluble

148
Q

vitamins, such as the B vitamins and vitamin C, dissolve in water. They are absorbed from the water in the intestinal tract and typically remain in
the body only a short time before being excreted in the urine.

A

Water-soluble

149
Q

Vitamins were discovered at the beginning of the twentieth century. They were found to be associated with
certain foods known to protect people from diseases such as

A

Rickets and beriberi

150
Q

are molecules, produced as part of normal metabolism, that are missing an electron.

A

Free radicals

151
Q

The loss of an electron from a molecule is called

A

Oxidation

152
Q

Free radicals can replace the missing electron by taking an electron from cell molecules, such as ______, ______, or ______, resulting in damage to the cell.

A

Lipids, Proteins, DNA

153
Q

Damage from free radicals may contribute to aging and certain diseases, such as

A

Atherosclerosis and cancer.

154
Q

substances called _________ may counteract these effects by donating an electron to free radicals and thus preventing the oxidation of cell components.

A

Antioxidants

155
Q

Examples of antioxidants are

A

Beta carotene (provitamin A), vitamin C, and vitamin E.

156
Q

RDA

A

Recommended Dietary Allowances

157
Q

which are the nutrient intakes sufficient to meet the needs of nearly all people in certain age and gender groups.

A

RDA

158
Q

consuming too much of some vitamins and minerals can be

A

Harmful

159
Q

the long-term ingestion of 3–10 times the RDA for _________ can cause bone and muscle pain, skin disorders, hair
loss, and an enlarged liver.

A

Vitamin A

160
Q

Consuming 5–10 times the RDA of _________ over the long term can result in calcium deposits in the kidneys, heart, and blood vessels

A

Vitamin D

161
Q

Consuming more than 2 g of ________ daily can cause stomach inflammation and diarrhea.

A

Vitamin C

162
Q

are inorganic nutrients that are necessary for normal metabolic functions.

A

Minerals

163
Q

The minerals are divided into two
groups

A

Major minerals and trace minerals

164
Q

The daily requirement for major minerals is _____ daily.

A

100 mg or more

165
Q

The daily requirement for trace minerals is ______ mg daily.

A

less than 100

166
Q

Minerals constitute about ____ of total body weight.

A

4-5%

167
Q

Some minerals are components of other important molecules in the body, such as

A

coenzymes, a few vitamins, and hemoglobin.

168
Q

are involved in a number of important functions, including establishing resting membrane potentials and generating
action potentials, adding mechanical
strength to bones and teeth, combining with organic molecules, and acting as coenzymes, buffers, and regulators of osmotic pressure.

A

Minerals

169
Q

People ingest minerals alone or in combination with organic molecules, as well as obtain them from both _____ and _____ sources.

A

Animal, plant

170
Q

Mineral absorption from _____ can be limited because the minerals tend to bind to plant fibers.

A

Plants

171
Q

are often added to refined breads and cereals to compensate for their loss during the refinement process.

A

Minerals and vitamins

172
Q

A _________ can provide all the vitamins and minerals required for good health for most people.

A

Balanced diet

173
Q

Some nutritionists, however, recommend taking a once-a-day multiple _________ supplement as insurance because many people’s diets are not balanced.

A

Vitamin and mineral

174
Q

are dietary values that appear on food labels to help consumers plan a healthful diet.

A

Daily values

175
Q

are based on the 1968 RDAs
for certain vitamins and minerals.

A

Reference Daily Intakes (RDIs)

176
Q

are set for total fat, saturated fat, cholesterol, total carbohydrate, dietary fiber, sodium, potassium, and protein.

A

Daily Reference Values (DRVs)

177
Q

RDIs have been set for four categories of people:

A

Infants, toddlers, people over 4 years of age, and pregnant or lactating women

178
Q

Therefore, the RDIs and DRVs were combined to form the

A

Daily Vales

179
Q

The Daily Values appearing on food labels are based on a ____ kcal reference diet, which approximates the weight maintenance requirements of postmenopausal women, women who exercise moderately, teenage girls, and sedentary men

A

2000

180
Q

On large food labels, additional information is listed based on a daily intake of ____ kcal, which is adequate for young men.

A

2500

181
Q

The Daily Values for energy-producing nutrients are determined as a percentage of daily kilocalorie intake:

A

60% for carbohydrates, 30% for total fats, 10% for saturated fats, and 10% for proteins.

182
Q

The Daily Value for fiber is 14 g for each ____ kcal of intake.

A

1000

183
Q

is the total of all the chemical
reactions that occur in the body.

A

Metabolism

184
Q

includes the energy-releasing process by which large molecules are broken down into smaller molecules.

A

Catabolism

185
Q

includes the energy-requiring process by which small molecules are joined to form larger molecules.

A

Anabolism

186
Q

of nutrients begins during digestion when large molecules, such as polysaccharides and fats, are broken down for absorption by the small intestine.

A

Catabolism

187
Q

The process of catabolism continues in the cells when the absorbed nutrients are further broken down for

A

ATP production

188
Q

The energy derived from catabolism is
used to drive _______ and processes such as active transport and muscle contraction.

A

Anabolic reactions

189
Q

occurs in all the body cells as they divide to form new cells, maintain their own intracellular structure, and produce molecules, such as hormones, neurotransmitters, and extracellular matrix molecules, for export.

A

Anabolism

190
Q

Most ATP from glucose is generated in the

A

Electron Transport Chain

191
Q

is a short-term energy-storage molecule that the body can store in LIMITED amounts

A

Glycolysis

192
Q

are long-term
energy-storage molecules that the body can store in LARGE amounts.

A

Lipids

193
Q

metabolism begins with _________, a series of chemical reactions in the cytosol that results in the break-down of glucose into two pyruvic acid molecules

A

Glycolysis

194
Q

Glycolysis is divided into four phases:

A
  1. Input of ATP
  2. Sugar Cleavage
  3. NADH Production
  4. ATP and Pyruvic Acid Production
195
Q

The first steps in glycolysis require the input of energy in the form of

A

Two ATP molecules

196
Q

An ATP molecule is used in the process called ___________, where a phosphate group is transferred from ATP to glucose. This first step forms glucose-6 phosphate.

A

Phosphorylation

197
Q

The glucose-6-phosphate atoms are rearranged to form

A

Fructose-6-phosphate

198
Q

A second ATP molecule is then used to phosphorylate fructose-6 phosphate, producing

A

Fructose-1,6-bisphosphate

199
Q

Fructose-1,6 bisphosphate is cleaved, or broken, into

A

Two 3-carbon molecules,
Glyceraldehyde-3-phosphate,
Dihydroxyacetone Phosphate

200
Q

Dihydroxyacetone phosphate
is rearranged to form a second _________; consequently, two molecules of _________ result

A

Glyceraldehyde-3-phosphate

201
Q

Each glyceraldehyde-3- phosphate molecule is oxidized (loses two electrons) to form

A

1,3 bisphosphoglyceric acid

202
Q

Nicotinamide Adenine Dinucleotide (NAD+) is reduced (gains
two electrons) to

A

NADH

203
Q

Glyceraldehyde-3-phosphate also loses _______, one of which binds to NAD+.

A

Two H+

204
Q

is referred to as an electron carrier molecule

A

NADH

205
Q

The last four steps of glycolysis produce (1) _______ molecules and (2) _______ molecule from each 1,3 bisphosphoglyceric acid molecule.

A

(1) Two ATP
(2) One pyruvic acid

206
Q

Since the previous step produced two 1,3-bisphosphoglyceric
acid molecules, this last step produces (1) _______ molecules
and (2) _______ molecules

A

(1) Four ATP
(2) Two Pyruvic Acid

207
Q

Each glucose molecule that enters glycolysis forms _____________ molecules at the sugar cleavage
phase.

A

Two
glyceraldehyde-3-phosphate

208
Q

Each glyceraldehyde-3-phosphate molecule produces
(1) _________, (2) __________, and (3) __________ molecule.

A

(1) Two ATP molecules
(2) One NADH molecule
(3) One pyruvic acid

209
Q

The breakdown of each glucose molecule, therefore,
produces (1) ________, (2) ________, and (3) _________ mole-
cules.

A

(1) Four ATP
(2) Two NADH
(3) Two Pyruvic Acid

210
Q

The start of glycolysis requires the input of two ATP molecules, the final yield of each glucose molecule is (1) ________, (2) ________, and (3) ________ molecules

A

(1) Two ATP
(2) Two NADH
(3) Two Pyruvic Acid

211
Q

If the cell has adequate amounts of oxygen, the NADH and pyruvic acid molecules are used in _________ to produce ATP.

A

Aerobic Respiration

212
Q

is the breakdown of glucose in
the absence of oxygen.

A

Anaerobic Glycolysis

213
Q

In human cells, the breakdown of a glucose molecule in the absence of oxygen produces two molecules of ________ and two molecules of ____

A

Lactate, ATP

214
Q

Anaerobic glycolysis can be divided into two phases:

A

Glycolysis
Lactate Formation

215
Q

is first converted to lactic acid, a reaction that requires the input of energy from the NADH produced in step 3 of glycolysis.

A

Pyruvic Acid

216
Q

In cells, lactic acid
usually releases a ____ and is converted to lactate, the ionized form of lactic acid.

A

H+

217
Q

Lactate is released from the cells that produce it, and blood transports it to the

A

Liver

218
Q

Thisprocess of converting lactate to glucose is called the

A

Cori Cycle

219
Q

The oxygen necessary for synthesizing the ATP is part of the

A

Oxygen Deficit

220
Q

Aerobic Respiration is the breakdown of glucose in the
presence of oxygen to produce

A

Carbon Dioxide
Water
36 ATP Molecules

221
Q

Most of the ATP molecules required to sustain life are produced through

A

Aerobic Respiration

222
Q

Aerobic Respiration can be considered in four phases:

A

(1) glycolysis (which is also the first phase of anaerobic glycolysis)
(2) acetyl-CoA formation
(3) the citric acid cycle
(4) the electron-transport chain

223
Q

Recall that glycolysis, the first phase, produces pyruvic acid. In the second phase of aerobic respiration, pyruvic acid is converted to ________, releasing carbon dioxide in the process.

A

Acetyl-Coa

224
Q

The pyruvic acid moves from the cytosol into a

A

Mitochondrion

225
Q

A mitochondrion is separated into the intermembrane space and the matrix by
the

A

Inner mitochondrial membrane

226
Q

Within the _______, enzymes remove a carbon and two oxygen atoms from the 3-carbon pyruvic acid molecule to form carbon dioxide and a 2- carbon acetyl group

A

Matrix

227
Q

The acetyl group combines with _________
(CoA) to form acetyl-CoA.

A

Coenzyme A

228
Q

For each two pyruvic acid molecules from glycolysis, _________ are formed

A

Two acetyl-CoA molecules
Two carbon dioxide molecules
Two NADH

229
Q

The third phase of aerobic respiration is the __________, which is named after the 6-carbon citric acid molecule formed in the first step of the cycle.

A

Citric Acid Cycle

230
Q

Citric acid cycle is also called the _______ after its discoverer, British biochemist Sir Hans Krebs.

A

Krebs Cycle

231
Q

The citric acid cycle begins with the production of citric acid. This occurs when the 2-carbon acetyl-CoA, produced in the second phase, combines with a 4-carbon molecule called

A

Oxaloacetic acid

232
Q

During the reactions of the
citric acid cycle, three important
events occur:

A

ATP Production
NADH and FADH2 Production
Carbon Dioxide Production

233
Q

The fourth phase of aerobic respiration involves the _____________, which is a series of electron carriers in the inner mitochondrial membrane.

A

Electron Transport Chain

234
Q

The H+ cannot simply diffuse down the concentration gradient but must pass through certain channels formed by an enzyme called

A

ATP Synthase

235
Q

As the H+ diffuses down the concentration gradient, energy is released that is used to produce ATP. This process is called ___________ because the chemical formation of ATP is coupled to a diffusion force similar to osmosis.

A

Chemiosmosis

236
Q

are the body’s main energy-storage molecules.

A

Lipids

237
Q

In a healthy person, lipids are responsible for about (1) ____ of the body’s energy storage, and (2) _______ accounts for about 1%.

A

(1) 99%
(2) Glycogen

238
Q

Although ________ serve as an energy source, they are not considered storage molecules because their breakdown normally involves the loss of molecules that perform other functions.

A

Proteins

239
Q

Triglycerides are the main lipid stored in _______ tissue

A

Adipose

240
Q

Between meals, when triglycerides are broken down in adipose tissue, some of the fatty acids produced are released into the blood, where they are called

A

Free Fatty Acids

241
Q

Other tissues, especially _____________, use the free fatty acids as a source of energy.

A

Skeletal muscle and the liver

242
Q

The metabolism of fatty acids occurs by ___________, a series of reactions in which two carbon atoms are removed from the end of a fatty acid chain to form acetyl-CoA.

A

Beta Oxidation

243
Q

Acetyl-CoA can enter the citric acid cycle and be used to generate

A

ATP

244
Q

Acetyl-CoA is also used in __________, the
formation of ketone bodies.

A

Ketogenesis

245
Q

Two acetyl-CoA molecules combine to form a molecule of __________, which is converted mainly into β-hydroxybutyric acid and a smaller
amount of acetone.

A

Acetoacetic acid

246
Q

Acetoacetic acid, β-hydroxybutyric acid, and acetone are called

A

Ketone Bodies

247
Q

Excessive production of ketone bodies is called

A

Ketosis

248
Q

Ketone bodies are acidic, if the increased number of ketone bodies exceeds the capacity of the body’s buffering systems, _______, a decrease in blood pH,
can occur

A

Acidosis

249
Q

Examples of conditions that increase lipid metabolism are

A

Starvation Impact,
Diets consisting mainly of proteins and lipids with few carbohydrates,
Untreated Diabetes Mellitus

250
Q

Ketone bodies
are excreted by the ________ and diffuse into the alveoli of the
lungs.

A

KIdneys

251
Q

The synthesis of nonessential amino acids usually begins with

A

Keto Acids

252
Q

Unlike glycogen and triglycerides, ________ are not stored in the body.

A

Amino acids

253
Q

is the inadequate intake of nutrients or the inability to metabolize or absorb nutrients.

A

Starvation

254
Q

Starvation has a number of causes, including

A

Prolonged fasting
Anorexia
Deprivation
Disease

255
Q

During the _____ phase of starvation, blood
glucose levels are maintained through the production of glucose from glycogen, lipids, and proteins.

A

First

256
Q

In the second phase, which can last for several weeks, ______ are the primary energy source.

A

Lipids

257
Q

The third phase of starvation begins when the lipid reserves are depleted and the body switches to _______ as the major energy source.

A

Proteins

258
Q

In oxidative deamination, or deaminization, an ________ is removed
from an amino acid (usually glutamic acid), leaving ammonia and a keto acid.

A

Amine Group

259
Q

Enzymes in the liver convert _______- (beverage alcohol) into
acetyl-CoA; in the process, two NADH molecules are produced.

A

Ethanol

260
Q

Each gram of ethanol provides ______ of energy.

A

7 kcal

261
Q

Chronic alcohol abuse can result in ________
of the liver, which involves lipid deposition, cell death, inflammation, and scar tissue formation.

A

Cirrhosis

262
Q

The body experiences
two major metabolic states:

A

Absorptive State
Postabsorptive State

263
Q

is the period immediately after a meal, when nutrients are being absorbed through the intestinal
wall into the circulatory and lymphatic systems

A

Absorptive State

264
Q

The absorptive state usually lasts about __ hours after each meal, though the rate of absorption declines after 1–2 hours.

A

4

265
Q

occurs late in the morning, late in the
afternoon, or during the night after each absorptive state is concluded

A

Postabsorptive state

266
Q

is the total amount of energy produced and used by the body per unit of time.

A

Metabolic Rate

267
Q

A molecule of ATP exists for less than _______ before it is degraded back to ADP and inorganic phosphate.

A

1 minute

268
Q

One liter of oxygen consumed by the body is estimated to produce ____ kcal of energy.

A

4.825

269
Q

A pound of body fat (adipose tissue) provides about
____ kcal.

A

3500

270
Q

Metabolic energy is used in three ways:

A

Basal Metabolism
Thermic effect of food
Muscular activity

271
Q

is the energy needed to keep the
resting body functional.

A

Basal Metabolic Rate

272
Q

A typical Basal Metabolic Rate
for a 70 kg (154-pound) male is

A

38 kcal/m2/h

273
Q

In the average person, basal metabolism accounts for about ___ of energy expenditure.

A

60%

274
Q

people have a higher BMR than
older people because of increased cell activity, especially during growth.

A

Younger

275
Q

Males have a greater BMR than
females because men have proportionately more (1) _______ tissue and less (2) _______ tissue than women do.

A

(1) Muscle
(2) Adipose

276
Q

During pregnancy, a woman’s BMR can increase ___ because of the metabolic activity of the fetus.

A

20%

277
Q

The second component of metabolic energy is used for activities
involved in digestion and absorption of food.

A

Thermic effect of food

278
Q

The energy cost of these events accounts for about ___ of the body’s energy expenditure.

A

10%

279
Q

consumes about 30% of the body’s energy.

A

Muscular Activity

280
Q

sometimes called
inborn errors of metabolism, are a large class of genetic disorders that result in
biochemical defects.

A

Metabolic Disorders

281
Q

is the total amount of energy liberated by the complete catabolism of food.

A

Free Energy

282
Q

The average normal __________- is considered to be
37°C (98.6°F) when measured orally and 37.6°C (99.7°F) when
measured rectally.

A

Body Temperature

283
Q

Our bodies exchange heat with the environment in a number of ways, including

A

Radiation
Conduction
Convection
Evaporation

284
Q

is the gain or loss of heat between two objects that are not in physical contact.

A

Radiation

285
Q

is the exchange of heat between objects in direct contact with each other, such as the bottoms of the feet and the floor.

A

Conduction

286
Q

is a transfer of heat between the body and
the air or water, as the air or water moves across the surface of
the skin.

A

Convection

287
Q

is the conversion of water from a liquid to a gas, a process that requires heat.

A

Evaporation

288
Q

is maintained by balancing heat gain with heat loss.

A

Body Temperature

289
Q

If heat gain exceeds heat loss, body temperature

A

Increases

290
Q

If heat loss exceeds heat gain, body temperature

A

Decreases

291
Q

Obesity can be further classified according to the number and size of

A

Adipocytes

292
Q

adipocytes are both more numerous
and larger than normal.

A

Hyperplastic Obesity

293
Q

results from a normal number of adipocytes that have increased
in size.

A

Hypertrophic Obesity

294
Q

This type of obesity,
which is associated with massive obesity, begins at an early age.

A

Hyperplastic Obesity

295
Q

This more common type of obesity is
associated with moderate obesity and typically develops in adults.

A

Hypertrophy Obesity

296
Q

Body temperature regulation is an example of a _________ system controlled by a set point.

A

Negative-feedback

297
Q

elevated body temperature, develops when heat gain exceeds the body’s ability to lose heat.

A

Hyperthemia

298
Q

Hyperthermia can result from

A

Exercise
Exposure to hot environments
Fever
Anesthesia

299
Q

is characterized by wet, cool skin due to heavy sweating.

A

Heat Exhaustion

300
Q

is more severe than heat exhaustion because it results from a breakdown in the normal negative-feedback mechanisms
of temperature regulation.

A

Heat Stroke

301
Q

is the development of a higher than normal body temperature due to invasion of the body by microorganisms or other foreign substances.

A

Fever

302
Q

Lymphocytes, neutrophils, and macrophages release chemicals called _________, such as certain interleukins,
interferons, and tissue necrosis factor.

A

Pyrogens

303
Q

In people who have the inherited muscle
disorder _______________, certain
general anesthetics cause sustained, uncoordinated muscle contractions.

A

Malignant Hyperthermia

304
Q

is an induced elevation in local or general body temperature
sometimes used to treat tumors and infections.

A

Therapeutic hyperthermia

305
Q

If heat loss exceeds the body’s ability to produce heat, body temperature falls below normal.

A

Hypothermia

306
Q

is a decrease in body temperature to 35°C (95°F) or below.

A

Hypothermia

307
Q

is sometimes
used to slow the metabolic rate during surgical procedures, such as heart surgery.

A

Therapeutic Hypothermia