Nutraceuticals

Question 1

Ephedra may cause adverse effects on which organ system?

Answer 1

heart

Question 2

Kava-kava may cause adverse effects on which organ system?

Answer 2

hepatotoxicity

Question 3

Comfrey may cause adverse effects on which organ system?

Answer 3

hepatotoxicity

Question 4

Germander may cause adverse effects on which organ system?

Answer 4

hepatotoxicity

Question 5

Green Tea Extract may cause adverse effects on which organ system?

Answer 5

hepatotoxicity

Question 6

Chaparral may cause adverse effects on which organ system?

Answer 6

hepatotoxicity, carcinogenicity

Question 7

Borage may cause adverse effects on which organ system?

Answer 7

hepatotoxicity, carcinogenicity

Question 8

Senna may cause adverse effects on which organ system?

Answer 8

hepatotoxicity, carcinogenicity

Question 9

Licorice may cause adverse effects on which organ system?

Answer 9

pseudo-hyperaldosteronism

Question 10

What metabolite of licorice causes its pseudo-hyperaldosteronism effects?

Answer 10

glycerrhizzin

Question 11

Which supplements may antagonize the effects of immunosuppressant medications like cyclosporine?

Answer 11

Echinacea and ginseng

Question 12

Which supplement contains estrogen-like compounds?

Answer 12

red clover

increased risk of breast CA, endometrial CA

Question 13

Which supplement may increase PSA doubling time in prostate cancer?

Answer 13

Pomegranate juice

but inhibits CYP and may increase rhabdo in statin use

Question 14

Which vitamins may antagonize warfarin?

Answer 14

E and K

Question 15

Benefits of omega 3 FAs?

Answer 15

increase both HDL and LDL

decreased risk of second MI + death from any cause, decreased risk of Alzheimer’s

Question 16

Benefits of CoQ10?

Answer 16

• maintain healthy muscle
• lowers BP
• improvements in HDL, exercise tolerance
• few side FX

-monitor warfarin tx

Question 17

Hormonal side effects of melatonin?

Answer 17

Decreased male and female fertility; decreased breast milk production

Question 18

There is good evidence for supplementation with garlic to do what?

Answer 18

to lower cholesterol

Question 19

There is good evidence for supplementation with ginseng to do what?

Answer 19

MAY provide benefit in CV disorders, decrease LDL cholesterol, decrease blood sugar, boost immune system

Question 20

Good evidence for supplementation with what to assist with symptoms of BPH?

Answer 20

beta-sitosterols