nucleotides + nucleic acids Flashcards

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1
Q

purine bases

A

adenine

guanine

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2
Q

pyramidine

A

cytosine
uracil
thymine

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3
Q

DNA

A

deoxyribose
A T C G bases - carbon 3
phosphate group - carbon 5

double stranded - antiparallel strands in a helix wound around histones
1 type of DNA

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4
Q

RNA

A

ribose
A U C G bases - carbon 3
phosphate group - carbon 5

single stranded
3 types - mRNA, tRNA, rRNA

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5
Q

sugar phosphate backbone

A

between phosphate at carbon 5 of pentode sugar and hydroxyl group on carbon 3 of the pentode sugar of adjacent nucleotide. Nucleotides joined by phosphodiester bonds

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6
Q

semi conservative DNA replication

A
  1. DNA helicase breaks H bonds between bases - leaving two single strands of DNA with exposed bases
  2. Free nucleotides bind to exposed bases by complementary base pairing
  3. DNA polymerase catalyses formation of phosphodiester bonds between adjacent nucleotides
  4. DNA ligase seals strand
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7
Q

why DNA replication

A
  • eliminates/ detects mutations

- conserves genetic information accurately through generations

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8
Q

gene

A

section of DNA which codes for a specific protein

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9
Q

features of genetic code

A
  1. triplet
    3 bases = 1 codon, every codon codes for an amino acid
  2. degenerate
    amino acids have more than 1 codon
  3. universal
    all organisms use same code, codons code for same amino acid
  4. non-overlapping
    each base part of only 1 codon (read in 3’s)
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10
Q

transcription

A
  1. DNA helicase unzips section of DNA containing gene by breaking H bonds
  2. sequence on antisense strand used to produce mRNA molecule
  3. free RNA nucleotides join your exposed bases on template strand by complementary base pairing
  4. RNA polymerase catalysed the formation of phosphodiester bonds between adjacent nucleotides
  5. Completed mRNA molecules leaves nucleus’s via pores
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11
Q

translation

A
  1. mRNA molecules binds to subunit on ribosome
  2. start codon read, tRNA molecule carrying amino acid with complementary anticodon binds to codon
  3. repeats
  4. peptidyl transferase catalyses formation of peptide bonds between adjacent amino acids forming a primary protein structure
  5. chain folds into secondary and tertiary structure
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