Nucleic Acids and Proteins Flashcards

1
Q

Biomacromolecules

A

large molecules made up of living organisms

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2
Q

Polymer

A

Made up of macromolecules and repeating subunits

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3
Q

Polymer examples

A
  1. polysaccharide
  2. polypeptide
  3. nucleic acid
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4
Q

Monomer

A

molecule that forms the basic unit for polymers

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5
Q

Monomer examples

A
  1. monosaccharide
  2. amino acid
  3. nucleotide
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6
Q

Condensation polymerisation

A

Monomer to polymer, releases water

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7
Q

Hydrolysis

A

polymer to monomer, requires water

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8
Q

Functions of Proteins

A

speeds up chemical reactions, cell recognition, cell communication, movement

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9
Q

Proteome

A

Complete set of proteins expressed by the genome of an individual

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10
Q

Proteomics

A

study of structure, functions and interactions of proteins

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11
Q

Protein Synthesis

A
  1. Primary Structure
  2. Secondary Structure
  3. Tertiary Structure
  4. Quaternary Structure
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12
Q

Primary Strucure

A

Sequence of amino acids. Monomers are joined by anabolic reactions which require energy

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13
Q

Secondary Structure

A

Folding of primary structures into alpha helices or beta pleated sheets

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14
Q

Tertiary Structure

A

the 3D shape of the protein determines its function.

hydrogen bonds, ionic bonds, covalent bonds, hydrophobic interactions

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15
Q

Quaternary Structure

A

2 or more polypeptide chains joined to form a functional protein

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16
Q

Nucleic Acids

A

responsible for carrying all genetic information of organisms and encodes the information for synthesis of protein in cells

17
Q

Bases

A

Nitrogen,
Purines - Adenine and Guanine
Pyrimidines - Cytosine, Thymine, Uracil

18
Q

DNA - deoxyribonucleic acid

A

Makes up genetic code, carries instructions for making proteins.
Strands run antiparallel, when nucleotide is added can only be added to 3’ end

19
Q

RNA - ribonucleic acid

A

Involved in every stage on gene expression.

transferRNA, ribosomalRNA, messengerRNA

20
Q

tRNA

A

Transfers amino acids from the cytosol to a ribosome

21
Q

rRNA

A

makes part of the ribosome, the site of translation

22
Q

mRNA

A

carries a transcription of genetic sequences to a ribosome for translation

23
Q

Gene expression

A

the process of transcribing and translating a genetic sequence into a gene product

24
Q

Triplet

A

a sequence of 3 DNA bases

25
Q

Codon

A

sequence of 3 mRNA bases

26
Q

Anticodon

A

sequence of tRNA bases

27
Q

Transcription

A

to copy a template strand of DNA into mRNA to carry instructions for a polypeptide chain to a ribosome

28
Q

Steps of transcription

A

DNA template > mRNA > polypeptide

  1. DNA partially unwinds, Helicase and Gyrase
  2. RNA primer binds at starting point
  3. RNA polymerase codes for complimentary strand of RNA
29
Q

Steps for Translation

A

mRNA > protein

  1. mRNA arrives at ribosome
  2. ribosome heads group of 3 nucleotides
  3. tRNA has specific anticodon complimentary to codons of mRNA
  4. peptide bond forms between joining amino acid, tRNA removed to be used again
  5. polypeptide production stops when “stop” sequence is reached