nucleic acids Flashcards

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1
Q

what elements are in nucleic acids

A
carbon
hydrogen
oxygen
nitrogen
phosphorous
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2
Q

name 3 components the makeup nucleotides

A
pentose monosaccharide (sugar) containing 5 carbon atoms
phosphate group- negatively charged
nitrogenous base- carbon rig +nitrogen
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3
Q

how are sugar phosphate backbones formed

A

phosphate group of 5th carbon on pentose sugar forms covalent bond with hydroxyl group 3rd carbon on another pentose sugar adjacent nucleotide
phosphodiester bonds

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4
Q

name the pentose sugar in RNA

A

ribose

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5
Q

name the pentose sugar in DNA

A

deoxyribose

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6
Q

name and describe pyrimidines

A

smaller bases with single carbon ring structure

  • cytosine
  • thymine- DNA
  • uracil- RNA
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7
Q

name and describe purines

A

larger bases with double carbon ring structure

  • adenine
  • guanine
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8
Q

what type of bond holds the 2 strands of polynucleotides together in a DNA helix

A

hydrogen

between bases

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9
Q

define antiparallel

A

the 2 strands run in opposite directions

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10
Q

(in DNA) which bases pair together

A

adenine+ thymine

guanine+ cytosine

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11
Q

what happens to DNA helix when cell prepares to divide

A

strands separate and act as template

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12
Q

how is complementary base pairing useful in DNA replication

A

ensures 2 new strands will be identical

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13
Q

describe semi-conservative replication

A

helix unwinds
free nucleotides pair with complementary base
hydrogen bonds form
nucleotides join adjacent ones forming phosphodiester bonds
each of 2 new mols reduced has 1 old and 1 new strand

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14
Q

what enzyme separates the 2 stands of DNA helix

A

DNA helicase

catalyses reactions that break hydrogen bonds between base pairs

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15
Q

wat enzymes helps form new strand

A

DNA polymerase

catalyses formation of phosphodiester bonds

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16
Q

what is the genetic code

A

DNA codes for sequence of amino acids in proteins

universal- same in all organisms

17
Q

what is a triplet code

A

sequence of 3 bases (codon) that codes for an amino acid

18
Q

explain the degenerate code

A

some amino acids coded for by more than 1 codon
only 1 start codon so code is non-overlapping
3 stop codons that don’t code for any amino acids
64 possible codons

19
Q

name the stand that codes for protein during transcription

A

sense strand

other is anti-sense

20
Q

what are the differences between transcription and replication

A

in transcription, RNA uracil binds to adenine

RNA polymerase catalyses formation of phosphodiester bonds

21
Q

what is the product of transcription

A

messenger RNA
detached from template and leaves through nuclear pore
DNA helix reforms

22
Q

what is translation

A

mRNA binds to smaller subunit of ribosome

decoded into sequence of amino acids

23
Q

what 3 types of activity do cells need ATP for

A

synthesis
transport
movement

24
Q

name structures in ATP

A

nitrogenous base (adenine)
pentose sigar
3 phosphate groups

25
Q

how does ATP release energy

A

hydrolysis occurs simultaneously with energy requiring reactions- releases energy
-forms ADP + phosphate ion