Nucleic Acids Flashcards
Fredrick Griffith
Heat killed S strain (virulent) mixed with benign strain killed the mouse
Suggests that the s strain passed on some information to the benign strand
Avery
wanted to find out if RNA DNA or proteins were responsible for transformation
Found that in extracts where DNA was killed, there was no transformation
Structure of DNA
Double helix Phosphate group 5 carbon deoxyribose sugar Nitrogenous base Phosphodiester bonds between two nucleotides
Purines
Adenine & guanine
Two rings
Pyrimidines
One ring
Cytosine and thymine
mRNA
Single stranded
Copy of gene that codes for a protein
Translated into proteins by ribosomes
tRNA
Folds into 3D structure held together by base pairing
Functional RNA that is never translated
Attaches to amino acids and brings them to ribosome during translation
rRNA
functional RNA
3 different molecules make up integral parts of ribosome
Form ribosome complexes that perform translation