Nucleic Acids Flashcards

1
Q

Nucleic acids are unbranched polymers composed of repeating monomers called

A

nucleotides

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2
Q

two types of nucleic acids:

A

DNA and RNA

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3
Q

stores the genetic information of an organism and transmits that information from one generation to another

A

DNA (deoxyribonucleic acid)

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4
Q

translates the genetic information contained in DNA into proteins needed for all cellular function

A

RNA (ribonucleic acid)

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5
Q

nucleotide monomers that compose DNA and RNA consist of_____

A

monosaccharide, a N-containing base, and a phosphate group

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6
Q

____ molecules contain several million nucleotides, while ____- molecules have only a few thousand

A

DNA & RNA

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7
Q

_____ is contained in the_____ of the nucleus, each chromosome having a different type of

A

DNA and chromosomes

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8
Q

How many chromosomes have humans

A

46 chromosomes (23 pairs),

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9
Q

What is the portion of the DNA molecule responsible for the synthesis of a single protein

A

genes

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10
Q

In RNA the monosaccharide is the_____

A

aldopentoseD-ribose

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11
Q

While, In DNA, the monosaccharide is the ____

A

aldopentoseD-2-deoxyribose

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12
Q

What element is the absence in D-2-deoxyribose

A

0H at C2

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13
Q

5 types of the N-containing base is

A

Cytosine (C), uracil (U), and thymine (T) are all based on the structure of pyrimidine

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14
Q

Give the two based on the structure of purine

A

Adenine (A) and guanine (G)

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15
Q

DNA contains bases

A

A, G, C, and T.

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16
Q

RNA contains bases

A

A, G, C, and U

17
Q

Is it true that a nucleoside is formed by joining the anomeric carbon of the monosaccharide with an N atom of the base

A

TRUE

18
Q

To name a nucleoside derived from a_____ , use the suffix “-idine

A

pyrimidine base

19
Q

To name a nucleoside derived from a ____, use the suffix “-osine”

A

purine base

20
Q

For ______ , add the prefix “deoxy-”

A

deoxyribonucleosides

21
Q

Nucleotides are formed by adding a _____to the 5′-OH of a nucleoside.

A

phosphate group

22
Q

The name____ is abbreviated as CMP

A

cytidine 5′-monophosphate

23
Q

The name _____ is abbreviated as dAMP

A

deoxyadenosine 5’-monophosphate

24
Q

What is the example of a diphosphate

A

ADP

25
Q

ATP is an example of a

A

triphosphate

26
Q

____ (DNA and RNA) are polymers of nucleotides joined by phosphodiester linkages

A

Nucleic acids

27
Q

A polynucleotide contains a backbone consisting of _____

A

alternating sugar and phosphate groups

28
Q

Is it true that the identity and order of the bases distinguish one polynucleotide from another (primary structure).

A

TRUE

29
Q

A polynucleotide has ___ at the 5’ end and___ at the 3’ end

A

one free phosphate group AND one free OH group

30
Q

In ___, the sequence of the bases carries the genetic information of the organism

A

DNA

31
Q

The DNA model was initially proposed by___ in 1953

A

Watson and Crick

32
Q

DNA consists of two polynucleotide strands that wind into a ___

A

right-handed double helix

33
Q

two strands run in____ directions

SAME / OPPOSITE

A

opposite

34
Q

TRUE/FALSE, sugar-phosphate groups lie on the outside of the helix and the bases lie on the inside.

A

TRUE

35
Q

____ pairs with thymine with 2 hydrogen bonds to form an A—T base pair

A

Adenine

36
Q

Cytosine pairs with___ using 3 hydrogen bonds to form a C—G base pair

A

guanine

37
Q

____ base pairs that always hydrogen bond together in a particular manner

A

complementary

38
Q

bases always line up so that a pyrimidine derivative can hydrogen bond to a purine derivative on the other strand. TRUE/ FALSE

A

TRUE