ENZYME

Question 1

Characteristics of Enzymes

Answer 1

Serve as biological catalysts, increase the rate of a reaction and, Enzymes are very specific

Question 2

names of most _____ end with the suffix

“-ase” like peptidase, lipase, and hydrolase

Answer 2

enzymes

Question 3

a metal ion or an organic molecule

needed for an enzyme-catalyzed reaction to occur

Answer 3

cofactor

Question 4

____ Is the cofactor (coenzyme) that oxidizes
lactate to pyruvate with the aid of the enzyme
lactate dehydrogenase

Answer 4

NAD+

Question 5

______ (S) attached to the reactive site of the

______ (E) forming an ES complex

Answer 5

Substrate and enzyme

Question 6

Type of Specificity

Answer 6

Absolute
Linkage
Group

Question 7

Catalyze one type of rxn

for a single substrate

Answer 7

Absolute

Question 8

Catalyze one type of rxn

for a single substrate

Answer 8

Group

Question 9

Catalyze one type of rxn

for a single substrate

Answer 9

Linkage

Question 10

_____ catalyzes only the

hydrolysis of urea

Answer 10

Urease

Question 11

______catalyzes
the hydrolysis of peptide
bonds

Answer 11

Chymotrypsin

Question 12

_______adds a
phosphate group to
hexoses

Answer 12

Hexokinase

Question 13

Two Models of Specificity

Answer 13

Lock-and-key model and Induced-fit model

Question 14

the active site is a rigid cavity

Answer 14

Lock-and-key model

Question 15

the active site has a flexible

shape

Answer 15

Induced-fit model

Question 16

Two types of Enzyme inhibition

Answer 16

Competitive Inhibition and Non-competitive Inhibition

Question 17

Interfere with active sites of the enzyme so substrate cannot bind

Answer 17

Competitive Inhibition

Question 18

Change the shape of the enzyme so it cannot bind to substrates

Answer 18

Non-competitive Inhibition

Question 19

are inactive forms of enzymes that can be converted to the active form when needed

Answer 19

Zymogens

Question 20

Drugs & Enzymes

Answer 20

Penicillin, ACE, HIV protease inhibitors

Question 21

Creatine phosphokinase

Answer 21

Heart attack

Question 22

Alkaline phosphatase

Answer 22

Liver or bone disease

Question 23

Acid phosphatase

Answer 23

Prostate cancer