nucleic acid and genetic info L4 Flashcards

1
Q

DNA —->mRNA=

A

transcription

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2
Q

mRNA—> protein=

A

translation

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3
Q

sugar of DNA

A

deoxyribose

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4
Q

bases of DNA

A

adenine- thymine

cytosine- guanine

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5
Q

RNA sugar

A

ribose

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6
Q

RNA bases

A

adenine- uracil

cytosine- guanine

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7
Q

nucleotides are made up off

A

pentose sugar
phosphate group
nitrogenous base

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8
Q

purine bases=

A

adenine, guanine

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9
Q

pyrimidine bases =

A

cytosine, thymine, uracil

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10
Q

other role of nucleotides

A

ATP carrier
signalling cAMP
enzyme cofactor

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11
Q

what is the directionality of DNA

A

5-3

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12
Q

what are the phosphate group and sugar group in adjacent nucleotides linked by

A

phosphodiester bonds

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13
Q

what bonds form between specific base pairs

A

hydrogen

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14
Q

what charged is phosphate groups

A

negative

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15
Q

where do you inherit mitochondrial DNA from

A

materally

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16
Q

how is DNA packaged

A

around histones

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17
Q

what is a nucleosome

A

a group of 8 histones

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18
Q

DNA is an acid or base

A

acid

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19
Q

Euchromatin=

A

unpacked beads on a string in a transcribing chromosome

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20
Q

heterochromatin=

A

packed fibre in a non-transcribing chromosome

21
Q

chromatin=

A

collection of nucleosomes

22
Q

what is within a chromosome

A

supercoiled chromatin fibre associated with non-histone proteins forming a chromosomal scaffold

23
Q

what determines the shape of a given chromosome

A

chromosomal scaffold

24
Q

centromere=

A

point of attachment to the mitotic spindle

25
chromatid
one copy of a duplicated chromosome
26
telomere=
protects the ends of the chromosome during replication
27
which arm is the short arm
P arm
28
which arm is the long arm
q arm
29
what is the human genome pattern
diploid
30
how many chromosomes
46
31
how many different autosomes
22
32
how many sex hormones
2
33
how many homologous pairs
23
34
when do chromosomes become visible
during replication
35
2 parts of cell cycle
division and interphase
36
3 parts of interphase
G1 S G2
37
what is the resting phase of a cell
G0
38
what happens in G1 phase
protein making and growing
39
what happens in S phase
chromosomes copied
40
what happens in G2
the cell checks DNA and gets ready to start dividing
41
cell division=
mitosis
42
5 phases of mitosis
``` prophase prometaphase metaphase anaphase telephase ```
43
what happen in prophase
chromosome condensation dispersal of nucleoli seperation of centrosomes and formation of mitotic spindle
44
what happens in prometaphase
fragmentation of the nuclear envelope attachment of spindle microtubles (MTs) to centromeres chromosomes start to move towards cell centre
45
what is the mitotic spindle formed from
micotubules
46
how do the microtubules attach to the centromere of the chromosome
via the kinetochore
47
what happens in metaphase
chromosome alingment at the metaphase plate
48
what happen in anaphase
chromosomes (chromatids) move to opposite cell poles
49
What happens in telephase
chromosomes uncoil nucleoli develope and fuse disassembly of spindle reformation of the nuclear envelope