Nuclear medicine for diagnosing oncological diseases Flashcards
Nuclear medicine for brai ntumors
FDG and PET scans. Increased uptake is proportional to malignancy.
Can be false positives for inflammation.
Low grade tumors may be hypo metabolic. and high grades are hyper.
Most common nuclear scan for oncology
FDG-PET whole body scan.
Especially FDG PET-CT
Majority of malignant tumors will be hyper active.
False positives include inflammatory processes.
Postoperative and postirradiation inflammation
Urinary accumulation and excretion
Bone marrow hyperplasia after chemotherapy
Thymus hyperplasia in young patients.
Other nuclear ligands to scan for different tumor types
DOPA - for neuroendocrine tumors
Octreotide - for neuroendocrine tumors
MIBG - adrenal receptor for pheochromocytoma
Iodine scintigraphy for well differentiated thyroid cancers
HIDA, or BrIDA compete with bilirubin for excretion, can determine whether lesions are funcitonal/nonfunctional, or if there is occlusion of any of the biliary tracts.
Other uses of nuclear medicien
Radioguided Occult Lesions Localization surgery
Where the radioligand is injected before surgery and then a handheld gamma probe is used by the surgeon to ensure it is all removed during the surgery,.
