Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Test 2 > NSAIDS > Flashcards

NSAIDS Flashcards

1
Q

Carprofen selectivity

A

No COX-1:COX-2 selectivity in clinical use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Carprofen used in what species

A

Only dogs, avoid in cats

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Carprofen problems

A
  • GI, renal, hepatic
  • higher incidence in Labs
  • wash out period before switch to any other NSAID
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ketoprofen selectivity

A

Has little to no COX-1:COX-2 selectivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ketoprofen approved in

A

Horses (non food), and dogs and cats.

-injectable only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Complications with ketoprofen

A
  • GI (dogs)

- GI/renal (horses)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Deracoxib class of inhibitors

A

Coxib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Deracoxib selectivity

A

Highly selective for COX 2 enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Deracoxib used in:

A

Dogs (post op pain)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Deracoxib contraindicated in:

A

Dogs with sulfonamide sensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Flunixin Medglumine selectivity

A

No COX 1 or COX 2 selectivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Flunixin megalumine used in

A

Horses, swine, cattle

- dogs are sensitive to GI damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Flunixin megalumine is limited by

A

Toxicity (<5 days)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Flunixin megalumine available as:

A

Injectable form for IV/IM or a metered paste

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

flunixin megalumine used for

A

Muscle pain, inflammation, pyrexia, colic, post op pain from de horning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Flunixin megalumine withdrawal time (dairy cattle, beef, veal,swine)

A
  • 36h
  • 4 days
  • NOT VEAL
  • 12d
17
Q

Phenylbutazone used in

A

Horses mainly but also dogs

18
Q

Phenylbutazone selectivity

A

Little Cox1/cox2 selectivity

19
Q

Phenylbutazone exhibits good ____ actions

A

Analgesic and antipyretic

20
Q

Phenylbutazone can’t be given by:

A

IM

21
Q

Can phenylbutazone be given to food animals

A

NOO

22
Q

Tepoxalin is a member of what class

A

Dual-acting agents which inhibit both CoX1 and cox2 as well as LOX
-all actions occur at clinical doses

23
Q

Topeoxalin inhibits formation of:

A

PGs, Txs, leukotrienes

24
Q

Topeoxalin approved for use in:

A

Dogs

Pharm Test 2 (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions