NSAIDs 2 Flashcards
Which NSAID can be used for patent ductus arteriosus?
Indomethacin
Indomethacin - adverse effects
GI and CNS effects (highest incidence of the NSAIDS)
Indomethacin - interactions
Triamterene: nephrotoxicity
NSAID with highest incidence of GI and CNS side effects
Indomethacin
Which NSAID has renal-sparing effect?
Sulindac
Sulindac - indications
Rheumatoid arthritis
Adenomas in polyp disease
NSAID with analgesic effect comparable with morphine
Ketorlac
Ketorlac - indications
Post-op in dentistry and ophthalmology
NSAID not used long term
Ketorlac - limited to 5 days treatment
Piroxicam - indications
Chronic rheumatoid arthritis
The only non-acid NSAID
Nabumetone
Diclofenac - indications
Osteoarthrits
COX2 inhibitors (1 drug)
Celecoxib
How does celecoxib differ from other NSAIDs?
No platelet aggregation inhibition
No GI toxicity
Which NSAID is associated with decreased risk for which cancer?
Celecoxib - colon cancer
