NS15 basal ganglia (Nuclei) and cerebellum Flashcards

1
Q

how does the cerebral cortex provide info?

A

Cerebral cortex says what is to be done

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2
Q

which structure has an input on how the action should be carried out in terms of quality and organisation of movement?

A

basal ganglia and cerebellum

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3
Q

what type of structures are basal ganglia?

A

grey matter structures

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4
Q

where does the basal ganglia receive and process info from?

A

cerebral cortex

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5
Q

where does the feedback from basal ganglia reach?

A

back to C.cortex via thalamus

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6
Q

is there any direct spinal cord connections between basal ganglia and cortex?

A

no, can only influence movement via cortex

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7
Q

List the components of the basal ganglia

A
internal capsule 
putamen 
Globus pallidus 
(subthalamic nucleus)
caudate nucleus
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8
Q

where would you find the caudate nucleus?

A

lateral ventricle

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9
Q

describe the connections of the basal ganglia?

A

listens processes then talks to motor cortex via thalamus

motor cortex –> Basal Ganglia
Basal Ganglia –> thalamus–> motor cortex

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10
Q

what is the first stage of the basic feedback circuit? (from motor cortex?)

A

putamen receives input from the motor cortex ‘‘talks’’ to globus pallidus

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11
Q

once GP receives info from stage 1, what happens in stage 2?

A

GP has a braking effect on thalamus (takes brake off)

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12
Q

once the GP has communicated to the thalamus, what happens next? (stage 3)

A

thalamus has a stimulatory drive on patterns of motor activity to cortex

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13
Q

where does the caudate Nucleus receive input from?

A

input from frontal cortex - planning organisation thought processes, not motor

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14
Q

how does the outer and inner segment of the GP communicate?

A

via the subthalamic nucleus

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15
Q

what does the subthalamus normally promote?

A

brake on thalamus and C.cortex

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16
Q

what is the effect of a hemiballismus?

A

weak brake on the thalamus
destruction of subthalamic nucleus
uncontrolled flailing movements

17
Q

List a couple of disorders of the basal ganglia

A

ballisumus - flailing limb movements at proximal joints

- parkinsons diease

18
Q

list 2 features of parkingsons disease

A

resting tremor
difficulty in initiating movement
depression

19
Q

what is the appearance like of substantia nigra in parkinsons disease compared to a normal midbrain section?

A

very minimal

20
Q

what are the functions of substantia nigra cells?

A

send processes to the putamen where they normally release dopamine

21
Q

list a treatment for parkinson’s disease

A

L-dopa - unlike dopamine crosses bloodbrain barrier