NS - CVS IV Flashcards
What 2 components are involved in cardiac circulation?
Coronary Arteries
- Carry oxygenated blood to the heart
- From aorta
Coronary Veins
- Carry deoxygenated blood to the right atrium
- From myocardium
How does blood return to the heart via veins?
Have very low resistance and pressures
Valves- one way flow
Where does fluid leakage occur?
Capillaries
What does the lymphatic system do?
Returns fluid from tissues to the bloodstream
Why does the CVS system need to be controlled?
Running the system is energetically expensive
What are 4 ways the CVS is regulated?
- Overall volume controls
- Control of local blood flow
- Control of venous return
- Control of cardiac output
How does the control of local blood flow regulate the CVS?
Regulation of flow to specific tissues occurs to meet metabolic demands
Main regulators
- Vasodilators
- Oxygen / nutrient lack
How does the control of venous return regulate the CVS?
Venous smooth muscle contracts to match BP demand
- Increases venous return
Slow- ADH (vasopressin), Renin-Angiotensin … cause vasoconstriction
Fast- Sympathetic signals/Circulating catecholamines
How does the control of cardiac output regulate the CVS?
Determines the amount of blood pumped by the heart per unit of time
Influenced by factors:
- Neuronal
- Hormonal
What is pre-load and how does it alter cardiac output?
The initial stretching of the cardiac myocytes prior to contraction
- Increased preload, Increased cardiac output
What is after-load and how does it alter cardiac output?
Force which the heart must pump against
- Increased afterload, decreased cardiac output
What involves the Nervous control of the heart?
Parasympathetic and Sympathetic
Where are Baroreceptors found and how do they function? (4)
Found in the aortic arch or carotid sinus
- Detect blood pressure changes
- Stimulate Na+ channels
- AP is signalled to Medulla Vasomotor Centre
- Parasympathetic or Sympathetic stimulated
Where are Chemoreceptors found and how do they function? (3)
Found in medulla surface / Aortic or Carotid bodies
- Detect H+ changes in medulla or O2 changes in bodies
- Chemoreceptors fire
- Parasympathetic or Sympathetic stimulated