NS

Question 1

Voltage gated channels

Answer 1

Change in electrical charge, hyper or de polarization

Axon

Question 2

Mechanically gated channels

Answer 2

Shape, soma

Receptors in muscles and change in shape

Question 3

Ligand gated channels

Answer 3

Chemicals, NT

Dendrite, soma
Post synaptic cell

Question 4

Components of action potential along neuron.

Answer 4

Receptor in muscle-> dendrite->soma-> axon hillock-> axon -> axon terminal

Question 5

Signal from input receptor to soma

Answer 5

• Signal picked up by the dendrite opens ligand gated channels
• depolarization of cell via large amount of Na moves into the neurolemna and k moves out
• continues along the dendrite and some until it reaches the axon hillock
• strength of signal depends on duration the LGC are open for or the number of LGC open
• signal needs to over come threshold in order to generate AP

Question 6

Axon hillock to axon terminal AP

Answer 6

• AP is an all or nothing response
• if threshold of 30 mV is reach at the AH the AP begins by opening ion specific VGC
• Na VGC open to depolarize cell
• K VGC open second and slowly close to create a hypo polarized axon= ensures AP in one directional
• # of Schwann cells determines how quickly the AP is conducted down axon

Question 7

PREsynaptic cell to postsynaptic cell

Answer 7

• AP reaching the axon terminal initiates the opening of Ca VGC and Ca enters the PREsynaptic cell
• Ca is responsible for bringing down the vesicles filled with NT, and released into the synaptic cleft via exocytosis
• NT bind to ligand receptors on the postsynaptic cell and initiate a response