Normocyctic Anemia

Question 1

What is the most important characteristic in aplastic anemia

Answer 1

-pancytopenia

Question 2

What are the causes of aplastic anemia

Answer 2

-constitutional (fanconi anemia)
-iatrogenic
-acquired (radiation, infection as EBV, Hepatitis virus, HIV, drugs as alkylating agent, antimetabolites, benzene, chloramphenicol)

Question 3

What are the symptoms of fanconi anemia

Answer 3

-cafe-au-lait
-short stature

Question 4

What is the immunosuppressive therapy given to the patient with aplastic anemia and why

Answer 4

-antithymocyte globulin + cyclosporine
-to decrease t-cell activity towards the bone marrow