Anemia Flashcards
What is anemia
-decrease O2 carrying capacity due to decrease of Hb concentration
What is the normal value of Hb in male
14-18
What is the normal value of Hb in female
12-16
What are the types of microcytic anemia
TAILS
-thalassemia (a or b)
-anemia of chronic disease
-iron deficiency anemia
-lead overload
-sideroblastic anemia
What are the types of macrocytic megaloblastic anemia
-folic deficiency
-B12 deficiency
What are the types of microcytic megaloblastic anemia
-liver disease
-alcoholism
-diamond-blackfan anemia
The blood presents with target cell
HALT
-HbC
-asplenia
-liver disease
-thalassemia
The blood presents with macro-ovalocyte (with polynucleated neutrophils)
-megaloblastic anemia
The blood presents with basophilic stipping (due to intact ribosomes)
-sideroblastic anemia
What are the main findings of extravascular hemolysis
-spelomegaly
-hepatomegaly
-<Hb
-<unconjugated bilirubin
-<Haptoglobin
->LDH
What are the main causes of extravascular hemolysis
-autoimmune hemolytic anemia
-hereditary spherocytosis
What are the main findings of intravascular hemolysis
-Hburia and hemosiderinuria
-hepatomegaly
-<Hb
-<unconjugated bilirubin
-<Haptoglobin
->LDH
What are the main causes of intravascular hemolysis
-complement (IgM)
-G6PD
-macroangiopathy
-microangiopathy (DIC, TTP, HUS)