Biochemistry Flashcards
1
Q
What is heme formed of and the bridges
A
-4 pyrrole rings (I, II, III, IV)
-4 methyne bridges (a, b, d, g)
2
Q
What is the rate limiting enzyme in heme synthesis
A
-ALA synthase
3
Q
What is the enzyme effected in sideroblastic anemia
A
-ALA synthase
4
Q
What is the enzyme effected in lead poisoning
A
-ALA dehydratase
-ferrochelatase
5
Q
What is the enzyme effected in acute intermittent porphyria
A
-uroporphorinogen I synthase
6
Q
What is the enzyme effected in cutaneous porphyria tarda
A
-uroporphyrinogen decarboxylase