Biochemistry Flashcards

1
Q

What is heme formed of and the bridges

A

-4 pyrrole rings (I, II, III, IV)
-4 methyne bridges (a, b, d, g)

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2
Q

What is the rate limiting enzyme in heme synthesis

A

-ALA synthase

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3
Q

What is the enzyme effected in sideroblastic anemia

A

-ALA synthase

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4
Q

What is the enzyme effected in lead poisoning

A

-ALA dehydratase
-ferrochelatase

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5
Q

What is the enzyme effected in acute intermittent porphyria

A

-uroporphorinogen I synthase

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6
Q

What is the enzyme effected in cutaneous porphyria tarda

A

-uroporphyrinogen decarboxylase

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