Normal Labour And Puerperium Flashcards
What is labour?
a physiological process during which the foetus, membranes, umbilical cord and placenta are expelled from the uterus
What factors are responsible for initiation of labour?
- Change in estrogen/progesterone ratio
- Fetal adrenals and pituitary hormones may control timing of the onset of labour
- Myometrial stretch increases excitability of myometrial fibres
- Mechanical stretch of cervix and fetal of membranes
- Ferguson’s reflex
What is Fergusons reflex?
a neuroendocrine reflex in which the foetal distension of the cervix stimulates a series of neuroendocrine responses, leading to oxytocin production
What hormonal factors influence onset of labour?
- Progesterone keeps the uterus settled - prevents formation of gap junctions, hinders the contractibility of myocytes
- Oestrogen makes the uterus contract and promotes prostaglandin production
- Oxytocin initiates and sustains contraction, acts on decidual tissue to promote prostaglandin release
- Oxytocin is synthesized directly in decidual and extraembryonic fetal tissues, and in the placenta
Other causes of labour onset?
- Pulmonary surfactant secreted into amniotic fluid has been reported to stimulate prostaglandin synthesis
- Increase in production of foetal cortisol stimulates an increase in maternal estriol
- Increase in myometrial oxytocin receptors and their activation results in phospholipase C activity and subsequent increase in cytosolitic calcium and uterine contractility
What cervical changes occur during labour?
- Cervical softening - increase in hyaluronic acid will decrease bridging among collagen fibres, decreasing firmness of the cervix
- Cervical ripening - changes include a decrease in collagen fibre alignment and strength, decrease in tensile strenght of the cervical matrix, and an increase in cervical decorin
What are the stages of labour?
First stage (consists of latent and active phases)
Second stage
Third stage
Latent phase of first stage of labour?
- mild irregular uterine contractions, cervix shortens and softens, duration variable
- May last a few days
Active phase of first stage of labour?
- 4cms onwards to full dilatation
- Slow decent of the presenting part
- Contractions progressviely become more rhythmic and stronger
- Normal progress is assessed at 1-2cms per hour
Second stage of labour?
- Starts with complete dilatation of the cervix fully dilated (10cms) to delivery of the baby
- In nulliparous (never given birth) women it is considered prolonged if it exceeds 3 hours if there is regional analgesia, or 2 hours without.
- In multiparous women it is considered prolonged if it exceeds 2 hours with regional analgesia or 1 hour without.
- In low risk care vaginal examinations are not always carried out to assess time of full dilatation
Third stage of labour?
- Delivery of the baby to expulsion of the placenta and fetal membranes, takes ~10 mins.
- After 1 hour, preparation made for surgical removal either by regional analgesia or under GA
- Expectant management - spontaneous delivery of the placenta.
- Active management - use of oxytocic drugs and controlled cord traction is preferred for lowering risk of post partum haemorrhage.
What influences contractions in labour
- Uterine muscle - smooth muscle in connective tissue, density highest at the fundus
- Pacemaker - region of tubal ostia, wave spreads in a downward direction
- Synchronisation of contraction waves from both ostia
- Polarity: upper segment contracts and retracts, lower segment and cervic stretch, dilate and relax
- Normal contractions have a fundal dominance with a regular pattern and adequate ‘resting tone’
What is tubal Ostia?
a translucent membrane lying at the junction between the intramural segment of the fallopian tube and the uterine cavity.
What is puerperium?
- Period of repair and recovery ~ 6 weeks involving return of tissues to non-pregnant state
- Bloodstained discharge lasts 10-14 days following birth
Clinical features of labour?
Brixton hicks contractions
True labour contractions
Signs of the third stage