Normal Labour and Peurperium Flashcards
What is labour?
A physiological process during which the fetus, membranes, umbilical cord and placenta are expelled from the uterus
What are the features of labour?
Regular, painful uterine contractions with increasing frequency, intensity and duration and accompanied biochemical changes in the cervical tissue allowing cervical effacement and cervical dilatation.
What are the 3 main factors for labour?
Power - uterine contractions
Passage - Maternal pelvis
Passenger - Fetus
In labour, what is the role of progesterone?
Keeps the uterus settled
Prevents formation of gap junctions
Hinders the contractibility of myocytes
In labour, what is the role of Estrogen?
Makes the uterus contract
Promotes prostaglandin production
In labour, what is the role of Oxytocin?
Initiates and sustains contractions
Acts on decidual tissue to promote prostaglandin release
Synthesised directly in decidual and extraembryonic fetal tissues and in the placenta
When does the number of oxytocin receptors increase?
In myometrial and decidual tissues near the end of the pregnancy
What Initiates labour?
Change in estrogen/progesterone ratio
Fetal adrenals and pituitary hormones may control the timing of onseet of labour
Myometrial stretch increases excitability of myometrial fibres
Mechanical stretch of cervix and stripping of fetal membranes
Fergusons reflex
What has been known to stimulate prostaglandin synthesis?
Pulmonary surfactant secreted into amniotic fluid
What happens in the 1st stage of labour?
Latent ohase up to 3-4cm dilation
Active stage 4cm - 10cm (full dilation)
Cervix shortens and softens, may be an uncomfortable few days
What happens in the 2nd stage of labour?
Full dilation - delivery of baby
Give analgesia
What happens in the 3rd stage of labour?
Baby is delivered
Expulsion of placenta and membranes
What active management is done to lower the risk of post partum haemorrhage?
Oxytocic drugs
Controlled cord traction
What else can be given in the 3rd stage of labour?
Prophylactic administration of syntometerine
1ml ampoule containing 500 micrograms ergometrine maleate and 5IU oxytocin
What causes an increase in molecules among collagen fibres?
Increase in hyaluronic acid
What causes cervical ripening?
Decrease in collagen fibre alignment
Decrease in collagen fibre strength
Decrease in tensile strength of the cervical matrix
Increase in cervical decorin (Dermatan sulphate proteoglycan 2)
What are Braxton Hicks contractions?
Tightening of the uterine muscles, thought to aid the body prepare for birth
When can Braxton Hicks start?
6 weeks into the pregnancy
Not usually felt till 2nd or 3rd trimester
How far apart do true contractions start?
5 mins
How will the abdomen feel during a contraction?
Hard
How does a contraction pain manifest itself?
Starts low and rises until it peaks and ebbs away
How do Braxton Hicks contractions manifest themselves?
Irregular, don’t increase in frequency or intensity
Resolve with ambulation or change in activity
Relatively painless