Norepinephrine

Question 1

Brand name for Norepinephrine

Answer 1

Leophed

Question 2

Drug class for Norepinephrine

Answer 2

Sympathomimetic, vasopressor

Question 3

Mechanism of action for Norepinephrine

Answer 3

Protine alpha 1 agonist, produces intense preipheral vasoconstriction, has 10% beta effect, Increaseing heart rate and force of contraction, resulting in an increase in SVR and CO

Question 4

Indications for Norepinephrine

Answer 4

Cardiogenic shock, shock unresponsive to fluid challenge, hypotensive patient’s with a systolic BP <70 mm/hg

Question 5

Contraindications for Norepinephrine

Answer 5

Hypovolemic shock

Question 6

Adverse effects of Norepinephrine

Answer 6

headache, anxiety, dizziness, restlessness, bradycardia, hypertension, chest pain, N/V, renal failure, peripheral cyanosis, tissue Necrosis with extravasation

Question 7

Precautions of Norepinephrine

Answer 7

deactivated by alkaline solutions, Bretylium May potentiate effects, other sympathomimetic drugs or phosphodiestrease inhibitors may exacerbate dysrhythmias

Question 8

dose for adults

Answer 8

0.1 - 0.5 mcg/kg/min infusion titrate to desired blood pressure

Question 9

dose for pedi

Answer 9

0.1 - 2 mcg/kg/min infusion, titrate to desired blood pressure