Eptifbatide Flashcards

1
Q

Brand name for Eptifbatide

A

Integrilin

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2
Q

Drug class for Eptifbatide

A

Glycoprotine IIb/IIIa inhibitor, platelet aggregation inhibitor

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3
Q

what is the mechanism of action for Eptifatide

A

Binds to glycoprotein IIb and IIIa receptros preventing the binding of fibrinogen

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4
Q

What are the indications for Eptifbatide

A

Unstable angina and patient’s undergoing percutaneous coronary intervention (PCI) used in conjunction with Heparin and Plavix

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5
Q

Contraindications for Eptifbatide

A

intracranial bleeding, intracranial neoplasm suspected aortic dissection, trauma within 3 months, surgical procedure within 3 weeks, low platelet count, hypertension

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6
Q

Adverse effects for Eptifbatide

A

head bleed, pulmonary hemorrhage, hypertension, GI bleeding

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7
Q

Precautions for Eptifbatide

A

Incompatible with Lasix, Effects increased with thrombolytic, oral anticoagulants, ASA, NSAID’s, sever bleeding

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8
Q

Dose for adults

A

180 mcg/kg over 1 to 2 minutes loading dose 2 mcg/kg infusion for 72 - 96 hrs

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9
Q

Dose for pedi

A

Not recommended for pedi

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