isoproterenol

Question 1

Brand name for Isoproterenol

Answer 1

Isuprel

Question 2

Drug class for Isoproterenol

Answer 2

Sympathomimetic, Bronchodilator

Question 3

Isoproterenol mechanism of action

Answer 3

Stimulates beta1- and beta2-receptors resulting in
relaxation of bronchial, GI, and uterine smooth muscle
increased heart rate and contractility, vasodilation
of peripheral vasculature

Question 4

Indications for Isoproterenol

Answer 4

Bronchoconstriction that is seen in asthma
COPD & chronic bronchitis, Used parenterally in ventricular arrhythmia due to A-V nodal block, temporary use in third degree A-V block until pacemaker insertion

Question 5

Contraindications for Isoproterenol

Answer 5

Angina, pre-existing cardiac arrhythmias,
tachycardia or A-V block caused by cardiac glycoside
Intoxication, allergy to sulfites or isoproterenol

Question 6

Adverse effects for Isoproterenol

Answer 6

Insomnia, restlessness, dry throat, xerostomia
flushing of the face or skin, ventricular arrhythmias
Nervousness, anxiety, dizziness, headache, diaphoresis
trembling, tremor, weakness, N/V

Question 7

Precautions for Isoproterenol

Answer 7

Sympathomimetic agents may cause headaches
and elevate blood pressure, general anesthetics may
cause cardiac arrhythmias

Question 8

Dose for bronchodilation of Isoproterenol

Answer 8

Inhalation: Metered dose inhaler: 1 - 2

metered doses 4 - 6 times/day

Question 9

Dose for Shock of Isoproterenol

Answer 9

I.V.: 0.5 - 5 mcg/minute; adjust according to

pt’s response