Noradrenaline synthesis, fate and metabolism Flashcards

1
Q

The “rest and digest” system is the ___

A

Parasympathetic NS

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2
Q

The external stimulus for the activation of the SNS is?

A

Stress

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3
Q

what neurotransmitter is released by sympathetic postganglionic fibres to sweat gland

A

acetylcholine

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4
Q

The kidney is supplied by what parasympathetic nerve

A

None
the kindney only has sympathetic supply

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5
Q

The PNS decreases rate of contraction of the whole heart
T or F

A

F
it only decreases rate of contraction of atria

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6
Q

The Parasympathetic NS inhibits glycogenolysis
T or F

A

F
the PNS does not supply the glycogen stores of the liver
and the adipose tissue

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7
Q

what is the effect of SNS and PNS insulin and glucagon secretion?

A

SNS inhibits insulin release and stimulates glucagon release
PNS stimulates release of both

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8
Q

In which organ are the effects of SNS and PNS not opposing to each other

A

Salivary gland

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9
Q

Blood vessels have both SNS and PNS supply
T or F

A

F
only SNS and the only blood vessels that receives supply are the arterioles and veins

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10
Q

the adrenal gland has receptors for what kind of neurotransmitter

A

acetylcholine

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11
Q

Adrenal cortex produces what kind of hormone

A

steroid hormones

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12
Q

The enzymes for processing cholesterol in the adrenal cortex are found in what organelles

A

smooth ER and inner mitochondria membrane (tubulovesicular mitochondria)

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13
Q

cholesterol used in the adrenal cortex is mostly gotten from?

A

endocytosis of LDL

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14
Q

the cells of the adrenal medulla are called

A

pheochromocytes

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15
Q

about 80% of hormone released by adrenal medulla is?

A

adrenaline

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16
Q

list the stimulus for catecholamine release into the blood stream

A

stress
intense light
low blood sugar
elevated sound levels

17
Q

what is the plasma concentration of L-tyrosine

A

1 - 1.5mg/dl

18
Q

what is the plasma ratio of norepinephrine to epinephrine

A

8:2
(yes despite the adrenal medulla secreting 80% epinephrin)

19
Q

alpha 1 receptors have a higher affinity for

A

norepinephrine
alpha 2 for norepinephrine

20
Q

B1 receptors have a higher affinity for?

A

Equal affinity for both epinephrine and norepinephrine

B2 has affinity for ONLY epinephrine