Nonhuman Primate Diseases Flashcards

1
Q

Mycobacterium tuberculosis causes what in the NHP?

A

tuberculosis

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2
Q

Mycobacterium bovis causes what in the NHP?

A

tuberculosis

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3
Q

TB

A

tuberculosis

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4
Q

Is TB common in wild monkeys?

A

No

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5
Q

How is Tb transmitted?

A
direct contact
secretions
aerosols
ingestion
fomites
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6
Q

Is TB more common in OWM or NWM?

A

OWM

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7
Q

Is TB common in prosimians?

A

no

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8
Q

Is TB asymptomatic in beginig stages?

A

yes

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9
Q

Is TB fatal in NHP?

A

yes

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10
Q

MOT

A

mammalian old tuberculin

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11
Q

How is TB diagnosed in NHPs?

A

intradermal TB test

MOT

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12
Q

What laboratory checks are required to identify the species of the TB bacterial causative agent ?

A

PCR

culture

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13
Q

What is the tx for TB in NHPs?

A

euthanasia

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14
Q

Is TB in NHPs zoonotic?

A

yes

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15
Q

is NHP herpes B virus fatal in humans?

A

yes

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16
Q

What kind of virus is the herpes B virus?

A

alphaherpesvirus

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17
Q

Herpesvirus simiae acauses what?

A

herpes B virus

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18
Q

How is herpes B virus transmitted?

A
secretions
innoculation
direct contact
fomites
aerosol
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19
Q

Can the herpes B virus be latent?

A

yes

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20
Q

Does vertical transmission occur with the herpes B virus?

A

no

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21
Q

Is herpes B virus currently recognized in Adircan monkeys?

A

no

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22
Q

What origin monkey is the natural reservoir for the herpes B virus?

A

asian maques

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23
Q

It is estimated that what percent of maques are herpes B virus carriers?

A

10-90%

24
Q

Can NHPs be infected with herpes B virus asymptomatically?

A

yes

25
Q

Can NHPs shed the herpes B virus even when asymptomatic?

A

yes

26
Q

In how many days do oral ulcers of monkeys infected with herpes B virus heal?

A

7-14d

27
Q

How is herpes B virus diagnoised?

A

lesions
serology
viral culture
PCR

28
Q

Is there are tx for NHPs infected with herpes B virus?

A

no

29
Q

Is herpes B virus zoonotic?

A

Yes

30
Q

What is the tx for NHPs with herpes B virus?

A

Euthanasia

31
Q

Individuals who survive the herpes B virus infection result with what?

A

Permanent CNS damage

32
Q

SIV

A

Simian immunodeficiency virus

33
Q

What kind of virus is SIV?

A

lentivirus

34
Q

What monkey species is the natural host for SIV?

A

macaques

35
Q

Does SIV have high prevelence in wild primates?

A

yes

36
Q

Does SIV have high prevelence in wild macaques?

A

no

37
Q

Is macaque SIV pathologic in other monkey species?

A

no

38
Q

What is the main consequence of SIV?

A

immunodeficiency

39
Q

Is SIV zonootic?

A

has potential for zoonosis

40
Q

What kind of virus is the monkey pox virus?

A

orthopox virus

41
Q

How is monkey pox transmitted?

A

contact

wounds

42
Q

Is monkey pox common to both NWM and OWM?

A

yes

43
Q

What does monkey pox lead to in NHPs?

A

lesions

44
Q

Can monkey pox result in organ necorsis and death?

A

yes

45
Q

Is monkey pox reportable?

A

yes

46
Q

Is monkey pox zoonotic?

A

yes

47
Q

What kind of microorganism is the Enterobius spp.

A

pinworm

48
Q

Enterobius spp. is a pinworm common in what kind of monkeys?

A

OWM

apes

49
Q

What kind of microorganism is the Trypanoxyuris spp.?

A

pinworm

50
Q

What kind of microroganism is the oxyuronema spp.?

A

pinworm

51
Q

Trypanoxyuris spp. and oxyuronema spp. pinworms are common what kind of monkeys?

A

NWM

52
Q

How is NHP pinworm transmitted?

A

orally

53
Q

What are the CS of NHP pinworm infection?

A

pruritus around anus

enteric dz

54
Q

How is NHP pinworm diagnosed?

A

tape test

55
Q

Is NHP pinworm zoonotic?

A

yes