Nonhuman Primate Diseases Flashcards

1
Q

Mycobacterium tuberculosis causes what in the NHP?

A

tuberculosis

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2
Q

Mycobacterium bovis causes what in the NHP?

A

tuberculosis

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3
Q

TB

A

tuberculosis

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4
Q

Is TB common in wild monkeys?

A

No

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5
Q

How is Tb transmitted?

A
direct contact
secretions
aerosols
ingestion
fomites
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6
Q

Is TB more common in OWM or NWM?

A

OWM

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7
Q

Is TB common in prosimians?

A

no

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8
Q

Is TB asymptomatic in beginig stages?

A

yes

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9
Q

Is TB fatal in NHP?

A

yes

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10
Q

MOT

A

mammalian old tuberculin

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11
Q

How is TB diagnosed in NHPs?

A

intradermal TB test

MOT

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12
Q

What laboratory checks are required to identify the species of the TB bacterial causative agent ?

A

PCR

culture

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13
Q

What is the tx for TB in NHPs?

A

euthanasia

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14
Q

Is TB in NHPs zoonotic?

A

yes

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15
Q

is NHP herpes B virus fatal in humans?

A

yes

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16
Q

What kind of virus is the herpes B virus?

A

alphaherpesvirus

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17
Q

Herpesvirus simiae acauses what?

A

herpes B virus

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18
Q

How is herpes B virus transmitted?

A
secretions
innoculation
direct contact
fomites
aerosol
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19
Q

Can the herpes B virus be latent?

A

yes

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20
Q

Does vertical transmission occur with the herpes B virus?

A

no

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21
Q

Is herpes B virus currently recognized in Adircan monkeys?

A

no

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22
Q

What origin monkey is the natural reservoir for the herpes B virus?

A

asian maques

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23
Q

It is estimated that what percent of maques are herpes B virus carriers?

24
Q

Can NHPs be infected with herpes B virus asymptomatically?

25
Can NHPs shed the herpes B virus even when asymptomatic?
yes
26
In how many days do oral ulcers of monkeys infected with herpes B virus heal?
7-14d
27
How is herpes B virus diagnoised?
lesions serology viral culture PCR
28
Is there are tx for NHPs infected with herpes B virus?
no
29
Is herpes B virus zoonotic?
Yes
30
What is the tx for NHPs with herpes B virus?
Euthanasia
31
Individuals who survive the herpes B virus infection result with what?
Permanent CNS damage
32
SIV
Simian immunodeficiency virus
33
What kind of virus is SIV?
lentivirus
34
What monkey species is the natural host for SIV?
macaques
35
Does SIV have high prevelence in wild primates?
yes
36
Does SIV have high prevelence in wild macaques?
no
37
Is macaque SIV pathologic in other monkey species?
no
38
What is the main consequence of SIV?
immunodeficiency
39
Is SIV zonootic?
has potential for zoonosis
40
What kind of virus is the monkey pox virus?
orthopox virus
41
How is monkey pox transmitted?
contact | wounds
42
Is monkey pox common to both NWM and OWM?
yes
43
What does monkey pox lead to in NHPs?
lesions
44
Can monkey pox result in organ necorsis and death?
yes
45
Is monkey pox reportable?
yes
46
Is monkey pox zoonotic?
yes
47
What kind of microorganism is the Enterobius spp.
pinworm
48
Enterobius spp. is a pinworm common in what kind of monkeys?
OWM | apes
49
What kind of microorganism is the Trypanoxyuris spp.?
pinworm
50
What kind of microroganism is the oxyuronema spp.?
pinworm
51
Trypanoxyuris spp. and oxyuronema spp. pinworms are common what kind of monkeys?
NWM
52
How is NHP pinworm transmitted?
orally
53
What are the CS of NHP pinworm infection?
pruritus around anus | enteric dz
54
How is NHP pinworm diagnosed?
tape test
55
Is NHP pinworm zoonotic?
yes