Lymphocytic Choriomeningitis Flashcards
Where does LCM originate from?
rodents
LCM
lymphocytic choriomeningitis
What kind of infectious agent is responsible for LMC?
virus
Define aseptic meningitis.
inflammation of the membrane, or meninges, that surrounds the brain and spinal cord
Define encephalitis.
Inflammation of the brain
Define mingoeningitis.
inflammation of both the brain and meninges
LMCV
lymphocytic choriomeningitis virus
Of what family is the LMCV?
Arenaviridae
Is an LMC infection without symptoms possible?
yes
Can fetuses contract LMC from an infected mother?
yes
What can an LMC infection in the fetus cause?
congenital hydrocephalus
chorioretinits
mental retardation
What is the primary host of the LMCV?
mouse
What is the genus and species of a mouse?
Mus musculus
What percent of mice in the U.S. is suspected to carry LMCV?
5%
Contact with what may transmit LMCV?
saliva
urine
feces
bedding
Do mice show signs of illness when infected with LMCV?
no
Is LMCV zoonotic?
yes
Can LMCV be transmitted via bite innoculation?
yes
Is human horizontal transmission of LMCV possible?
no
What is the percent of infection of LMCV in humans?
2%-5%
In humans what is the onset of symptoms of LMCV?
8-13 days
When does the secondary stage of LMCV infection begin?
a few days after recovery from first stage
How long can first stage of LMCV last?
1 week
Can LMCV cause hydrocephalus?
yes
