Lymphocytic Choriomeningitis Flashcards

0
Q

Where does LCM originate from?

A

rodents

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1
Q

LCM

A

lymphocytic choriomeningitis

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2
Q

What kind of infectious agent is responsible for LMC?

A

virus

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3
Q

Define aseptic meningitis.

A

inflammation of the membrane, or meninges, that surrounds the brain and spinal cord

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4
Q

Define encephalitis.

A

Inflammation of the brain

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5
Q

Define mingoeningitis.

A

inflammation of both the brain and meninges

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6
Q

LMCV

A

lymphocytic choriomeningitis virus

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7
Q

Of what family is the LMCV?

A

Arenaviridae

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8
Q

Is an LMC infection without symptoms possible?

A

yes

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9
Q

Can fetuses contract LMC from an infected mother?

A

yes

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10
Q

What can an LMC infection in the fetus cause?

A

congenital hydrocephalus
chorioretinits
mental retardation

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11
Q

What is the primary host of the LMCV?

A

mouse

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12
Q

What is the genus and species of a mouse?

A

Mus musculus

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13
Q

What percent of mice in the U.S. is suspected to carry LMCV?

A

5%

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14
Q

Contact with what may transmit LMCV?

A

saliva
urine
feces
bedding

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15
Q

Do mice show signs of illness when infected with LMCV?

A

no

16
Q

Is LMCV zoonotic?

A

yes

17
Q

Can LMCV be transmitted via bite innoculation?

A

yes

18
Q

Is human horizontal transmission of LMCV possible?

A

no

19
Q

What is the percent of infection of LMCV in humans?

A

2%-5%

20
Q

In humans what is the onset of symptoms of LMCV?

A

8-13 days

21
Q

When does the secondary stage of LMCV infection begin?

A

a few days after recovery from first stage

22
Q

How long can first stage of LMCV last?

A

1 week

23
Q

Can LMCV cause hydrocephalus?

A

yes

24
Q

Define hydrocephalus?

A

Increased fluid in the brain

25
Q

Do human patients usually recovery completely from LMC?

A

yes

26
Q

Is LMC normally fatal in humans?

A

no

27
Q

What is the mortality rate of LMC in humans?

A

1%

28
Q

Can pet rodents contract LMC from wild rodents?

A

yes