non opiate analgesics Flashcards
this blocks the N-methyl-D-aspirate (NMDA) receptor in the spinal cord that is involved in modulation and increased pain hypersensitivity (windup)
ketamine
these have a RELATIVELY short duration of action
locals
these provide good analgesia
alpha-2 agonists
this is typically admin as a CRI in combo with an opioid
ketamine
these all relieve somatic pain, and some relieve visceral pain too
NSAIDs
these have a potential for toxicity with repeated doses
locals
this is a non-opiate drug that stimulate the mu receptor
tramadol
these have a short duration of effect
alpha-2 agonists
GI and renal adverse effects are possible with these
NSAIDs
this is admin PO for continuation of pain management at home
tramadol
do not use these in combo with glucocorticoids - they both cause GI upset and ulcer formation
NSAIDs
there are no veterinary label tablets for this drug
tramadol
these have a profound sedative effect
alpha-2 agonists (major CV and respiratory depression)
these have potential adverse effects on the respiratory and CV systems
alpha-2 agonists
this works well with NSAIDs
tramadol