Injectable anesthetics: Ultra short-acting barbiturates

Question 1

2 examples of Ultra short-acting barbiturates (and if they’re short or long acting)

Answer 1

• pentobarbital (short-acting)

- phenobarbital (long-acting)

Question 2

main ingredient in euthanasia solutions

Answer 2

pentobarbital

Question 3

this helps control seizures

Answer 3

pentobarbital

Question 4

2 effects of Ultra short-acting barbiturates

Answer 4

• respiratory system depression

- cardiovascular depression

Question 5

Ultra short-acting barbiturates have a (more/less) profound effect on hypOproteinemic patients

Answer 5

more profound - less proteins to bind to means that there are more free drug molecules that go into other tissues and produce more of an effect

Question 6

Ultra short-acting barbiturates have a (more/less) profound effect on ACIDotic animals

Answer 6

more profound

Question 7

a low pH causes what?

Answer 7

a low pH causes the drug molecules to not bind to proteins as much as they normally would (so more profound effect)

Question 8

effect of Ultra short-acting barbiturates on lean animals (sight hounds)

Answer 8

they metabolize the drug more slowly

Question 9

Ultra short-acting barbiturates can cause:

Answer 9

tissue irritation - outside the vein - sloughing

Question 10

Ultra short-acting barbiturates are (stable/unstable) in solutions

Answer 10

unstable

Question 11

lean animals metabolize Ultra short-acting barbiturates more (faster/slowly)

Answer 11

slowly