non-operative management of lung cancer

Question 1

what is adjuvant therapy?

Answer 1

therapy after surgery to attempt to increase chance of survival

Question 2

what is neoadjuvant therapy?

Answer 2

therapy before surgery to attempt to increase chance of survival

Question 3

does adjuvant radiotherapy increase survival in stage I and II NSCLC patients?

Answer 3

no it is detrimental unless there is spread to mediastinal nodes or involves margins.

Question 4

is neoadjuvant chemotherapy advantageous in stage III NSCLC?

Answer 4

yes

Question 5

in patients with stage III NSCLC is survival rate better with just RT or with chemoRT?

Answer 5

with chemoRT

Question 6

is stage IV NSCLC curable?

Answer 6

no

Question 7

what is the treatment of stage IV NSCLC?

Answer 7

palliative treatment:

• RT to primary tumour
• systemic (chemo-) therapy is equally effective at relieving symptoms

Question 8

how many cycles of chemotherapy are given to patients with stage III and IV chemotherapy?

Answer 8

3 cycles is as good 6, but 4 is the average in UK

Question 9

what can cause bone pain in lung cancer?

Answer 9

bone mets

Question 10

what is the palliative therapy for bone mets?

Answer 10

radiotherapy
orthopaedic surgery
neurosurgeons for cord compression

Question 11

what is limited disease in SCLC?

Answer 11

disease staged to one hemithorax

Question 12

what is the treatment of choice for limited disease SCLC?

Answer 12

chemotherapy

or early thoracic RT

Question 13

what is the management of extensive disease SCLC?

Answer 13

4 cycles of combination chemotherapy