Non Odontogenic Cysts Flashcards

1
Q

Fissural Cysts

(6)

A

❑ Nasolabial cyst
❑ Globulomaxillary cyst (historic)
❑ Nasopalatine (incisive canal) cyst
❑ Incisive papilla cyst
❑ Median palatal cyst
❑ Median mandibular cyst (historic)

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2
Q

where a number of the visual cysts would develop

A

(1) That’s the nasopalatine, which is sort of up in the labial nasal fold and it’s in the soft tissue.
(2) Sort of where the nasal alveolar cyst would occur.
(3) Where the globular maxillary cyst would occur between the canine and the lateral sometimes between the lateral and the first premolar
(4) The nasopalatine in the cyst of the nasopalatine papilla
(5) Is the median palatal

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3
Q

Nasolabial Cyst

also known as

A

aka Nasoalveolar cyst

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4
Q

Nasolabial Cyst

Etiology

A

■ Thought to be caused by:

  • either epithelial remnants of the nasolacrimal duct
  • or cells left after fusion of the maxillary, medial and lateral nasal processes during development of the midface
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5
Q

Nasolabial Cyst

Location

A

Rare soft tissue cyst of the upper lip, lateral to the midline (right under the ala of the nose) *NOT in bone*

■ Clinically see a swelling which can cause elevation of the ala of the nose ■ Intraorally see a swelling in the maxillary vestibule lateral to the midline (usually sort of in the canine area or just a little bit distal to the canine area) ■ Pain is uncommon, unless cyst becomes infected

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6
Q

Nasolabial Cyst

Clinically & Intraoray

A

■Clinically we see a swelling which can cause elevation of the ala of the nose

■ Intraorally see a swelling in the maxillary vestibule lateral to the midline (usually sort of in the canine area or just a little bit distal to the canine area)

Pain is uncommon, unless cyst becomes infected

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7
Q

Nasolabial Cyst

Demographics

A

■ Peak in 4th and 5th decades

3 to 4 times more common in females

■ ~ 10% of cases are bilateral

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8
Q

Nasolabial Cyst

Histologically

A
  • We see a pathologic space lined with pseudostratified columnar epithelium
  • often with cilia and goblet cells
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9
Q

Nasolabial Cyst

Treatment

A
  • Surgical Excision via intraoral approach,
  • usually do not recur ~ very low risk of occurrence
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10
Q

_Nasolabial Cys_t has a a respiratory type epithelium and so it’s very similar to what you would see in ?

A

either in the sinus or in the nasopalatine ducts

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11
Q
A

Nasolabial Cyst

The lesion here just below the nose and you can tell that it’s sort of raising the edge of the nose slightly

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12
Q
A

Nasolabial Cyst

the lesion raising the edge of the nose slightly

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13
Q
A

Nasolabial Cyst Histology

✎When you look at the cyst itself, you can see that there’s a fibrous connective tissue wall and pathologic space that you see in the middle

✎The lining of the cysts looks like pseudostratified columnar epithelium with cilia which is classic for respiratory epithelium

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14
Q
A

Nasolabial Cyst Histology

✎On a high power you see pseudostratified columnar with cilia on the surface and so that’s respiratory epithelium

The connective tissue has a little bit of surgical hemorrhage

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15
Q

“Globulomaxillary Cyst”

Origin controvesy

why the name in quotations?

A
  • it’s in quotations, because really there is no such thing as a globulomaxillary cyst
  • because it was thought that this was remnants after fusion of the globular portion of the nasal process with the maxillary process, and now we know that these two processes are always united from the start and that there is no fusion
  • When biopsied these cysts are odontogenic in origin
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16
Q

what does it mean for Globulomaxillary Cyst to be odontogenic in origin?

A

✎This is term used to describe a cyst in a particular anatomic location it is not a diagnosis

✎An odontogenic cyst (inflammatory cyst, lateral periodontal or even sometimes OKC) that forms in the area between the maxillary lateral incisor and the canine roots

~ It’s really associated with a_n anatomic location not with any particular cyst._

✎So it can be any of the odontogenic lesions such as lateral granulomas or cysts, OKCs, COCs, etc.

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17
Q

Globulomaxillary Cyst

Radiographically

A

✎Presents as a “inverted pear” shaped well-circumscribed radiolucency

✎Frequently causes displacement of the roots

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18
Q

Is this

Globulomaxillary Cyst

lateral granulomas

OKCs

COCs

A
  • we can see the displacement of the root
  • A teardrop or pear shaped radiolucency between the lateral and the canine
  • Well circumscribed maybe leaving a little sclerotic edge up here
  • ended up being in a odontogenic keratocyst (OKC)
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19
Q

Is this Globulomaxillary Cyst , lateral granuloma or OKC?

A

~ it is kind of a teardrop or pear shaped size

~Little less well differentiated in this particular instance but again unilocular radiolucency between the roots of two teeth

This one ended up being an OKC

20
Q

Most common non-odontogenic cyst of the oral cavity

A

Nasopalatine Duct Cyst

21
Q

Nasopalatine Duct Cyst

also known as

A

incisive canal cyst

nasopalatine canal cyst

22
Q

Nasopalatine Duct Cyst

Origin

A
  • arise from epithelial remnants of the nasopalatine duct which, embryologically, connects the oral and the nasal cavities
23
Q

Nasopalatine Duct Cyst

Demographic and Location

A
  • Peak presentation in the 4th to 6th decades, but can occur at any age ~ because it takes a little bit of time for the cyst to grow within the bone
  • commonly found on the anterior palate ~ typically in the nasal area of the papilla.
24
Q

Nasopalatine Duct Cyst

Clinically

A

■ present with swelling o_f the anterior palate_ (in the nasal area of the papilla)

■ Most are asymptomatic, but they may have pain or drainage

25
Q

What are two different ways nasopalatine duct cyst arise?

A
  • *A**. It can either be the cyst totally within bone
  • *B**. It can actually cause widening of the orifice and causing the soft tissue expansion in this way
26
Q

Nasopalatine Duct Cyst

Radiographically

A

■ a well-circumscribed unilocular radiolucency on the midline of the anterior hard palate
between and apical to the central incisors
■ The radiolucency often have an oval or inverted pear shape with a sclerotic border
■ Superimposition with the nasal septum can create an appearance of the classic “heart” shape

27
Q

Cysts of the incisive papilla

Incisive papilla cyst

A

Is a soft tissue cyst (no bone involvement) located in
the same area as the Nasopalatine Duct Cyst

on the midline of the anterior hard palate
between and apical to the central incisors

. They may be symptomatic or asymptomatic and usually are not seen radiographically.

some consider them to be uncommon variants of the nasopalatine duct cysts

28
Q

Nasopalatine Duct Cyst
Histologically

A

■ the lining of the cyst can vary from SSE to pseudostratified columnar to simple columnar to
cuboidal

Cilia and goblet cells may be present (indications of respiratory epithelium)
■The fibrous connective tissue wall contains moderate sized nerve bundles and small muscular walled arteries and
vein
s (represents the nasopalatine neurovascular bundle ) ~ ■The fibrous connective tissue wall should show you
remnants of what the canal contained

29
Q

Nasopalatine Duct Cyst

Treatment

A
  • surgical excision
  • recurrence is rare
30
Q
A

Nasopalatine Duct Cyst

✎This person is edentulous
an inverted pear shape
✎The nasal spine is superimposed
on your radiolucency ► a heart shape

31
Q
A

Nasopalatine Duct Cyst

✎Between the roots of the two teeth, a well circumscribed
radiolucency, not showing any changes to the adjacent structures
✎could be an enlargement of the incisive canal due to variation in size ~ early lesions can be hard to diagnose
the treatment in such cases: a follow up with another radiograph in six months to see if there’s been any change in size
✎ No surgical intervention until you see the cyst expanding

32
Q
A

This is showing you the how the
papilla can be enlarged if it’s only
in soft tissue or if there’s a partial
soft tissue partial bone expansion

Nasopalatine Duct Cyst

33
Q
A

Nasopalatine Duct Cyst
Histology

Within the connective tissue wall, you can see this is
a nerve bundle and then we have these sort of thick
walled vessels some are arteries and some are veins

34
Q
A

Nasopalatine Duct Cyst
Histology

This is showing you the cilia in the columnar
epithelium with a little bit of cuboidal epithelium on
the basal aspect of it that was the lining of the cyst for
nasopalatine duct cysts

35
Q

Median Palatine Cyst

is

a variant of which cyst?

A

nasopalatine duct cyst

  • it represents a more posteriorly placed nasopalatine duct cyst
  • ~ It’s probably due to some sort of anatomic variation in the patients; that their palatine duct is just placed more posteriorly
  • So instead of being between the roots of these two teeth, it’s placed more posteriorly
36
Q
A

Median Palatine Cyst

37
Q

Median Mandibular Cyst

A
  • A controversial cysts whose existence is questioned ~ similar to the globulomaxillary cyst

■ Originally thought to arise from the fusion of the “halves” of the mandible, but current embryology finds that
the mandible forms from a single bilobed process, therefore, no epithelial remnants would be found

■ Now, it is thought that cysts in this area represent odontogenic cysts or tumors

  • Median Mandibular Cyst is a term used to describe a cyst in a particular anatomic location not a definitive diagnosis
    • ~ It is other lesions that occur in that particular location
    • The Anterior Mandible
38
Q

Is this Median Mandibular Cyst

Or something else

A

Remember

Median Mandibular Cyst is a term used to describe a cyst in a anterior mandible not a definitive diagnosis

So, this turned out to be an early ameloblastoma. It wasn’t a cyst

The lesion radiolucency in the anterior mandible and again

39
Q

Surgical Ciliated
Cyst of the Maxilla

Etiology

A

■ Occurs after trauma or sinus surgery (iatrogenic - reactive not neoplastic)

40
Q

Surgical Ciliated
Cyst of the Maxilla

Formation

A

■a portion of the sinus lining is separated from the sinus and forms an epithelial lined cavity in bone
■ Cavity fills with mucin produced by the mucous cells of the cyst lining
■ These cysts enlarge as the intraluminal pressure increases, causing destruction of bone

41
Q

Surgical Ciliated
Cyst of the Maxilla

occurs frequently

after

which procedures?

A
  • after a Caldwell-Luc procedure
  • sometimes with difficult maxillary extractions
42
Q

In which country Surgical Ciliated
Cyst of the Maxilla

are reported with higher frequency ?

A

Japan

43
Q
A

Surgical Ciliated
Cyst of the Maxilla

In this premolar shot (middle image) you can see a well-circumscribed lesion
✎Because the maxillary sinus is radiolucent, it almost looks like this is radiopaque but it’s not
✎ If you did a CBCT you would see that it’s an empty space within the bone of the maxilla. It’s not actually radiopaque

44
Q
A

Surgical Ciliated
Cyst of the Maxilla

HISTOLOGY

-the cyst lining

45
Q
A

Surgical Ciliated
Cyst of the Maxilla

histology

Then this is respiratory epithelium.

  • There is mucus within the cyst (red), lumen, fibrous connective tissue wall like all the cysts have