Non-Malignant Pain part 1 Flashcards

1
Q

What is pain?

A

An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.

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2
Q

What does the ‘PQRSTU’ mnemonic stand for in pain assessment?

A
  • Palliative or Precipitating factors
  • Quality of pain
  • Region of pain location
  • Severity (pain assessment instruments)
  • Time-related nature of pain
  • Impact of pain on you
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3
Q

List the objective information used to assess pain.

A
  • Behavioral changes
  • Physiological changes
  • Dilated pupils (mydriasis)
  • Paleness (pallor)
  • Sweating (diaphoresis)
  • Tachycardia
  • Tachypnea
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4
Q

What are the pain intensity scales used in pain assessment?

A
  • Verbal
  • Numeric
  • Visual
  • Wong-Baker
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5
Q

Who do the CDC guidelines for prescribing opioids apply to?

A

Outpatients aged ≥18 years with acute, subacute, or chronic pain.

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6
Q

What is the recommended dosing for acetaminophen (Tylenol) in adults?

A

325 -1000mg PO Q4-6H PRN (max dose ≤3-4 g/day).

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7
Q

What are some side effects of acetaminophen?

A

Hepatotoxicity, particularly with doses ≥10g.

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8
Q

What are the side effects of NSAIDs?

A
  • GI bleeding (black box warning)
  • Nephrotoxicity
  • Fluid retention
  • Increased CV events (black box warning)
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9
Q

What is Reye’s syndrome and with which medication is it associated?

A

A rare but serious condition causing brain and liver swelling, associated with children/teens using aspirin during viral infections.

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10
Q

What is the maximum recommended duration for ketorolac (Toradol) use?

A

5 days (for combined parenteral and oral use).increased risk of GI bleed when used longer

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11
Q

What is the recommended dosing for ibuprofen (Advil, Motrin) in adults?

A

200-800mg PO q6-8h PRN (max 3200mg/day).

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12
Q

Which NSAID is COX-2 selective and has less GI toxicity?

A

Celecoxib (Celebrex).

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13
Q

Fill in the blank: The recommended dosing for acetaminophen in pediatric patients is _______.

A

10-15 mg/kg PO Q4H PRN (max dose 75mg/kg/day or ≤3-4 g/day).

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14
Q

True or False: Acetaminophen is the gold standard for osteoarthritis due to fewer side effects in geriatric patients than NSAIDs.

A

True

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15
Q

What should be avoided in patients taking blood thinners or antiplatelets?

A

Aspirin (Bayer).

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16
Q

What are the available formulations of naproxen (Aleve, Naprosyn)?

A
  • Capsule
  • Tablet
  • DR/ER tablet
  • Suspension
17
Q

What is the maximum recommended dose of aspirin (Bayer) for adults?

18
Q

List the available formulations of diclofenac (Voltaren).

A
  • Capsule
  • Tablet
  • IV solution
  • Suppository
  • Topical gel
  • Topical solution
  • Ophthalmic solution
  • Patch
19
Q

What are non-pharm therapy options

A

Can be used in combination with analgesics
Physical manipulation
Heat or Ice
Massage
Acupuncture
Exercise
Correct the underlying cause (surgery, avoidance)

20
Q

What is a treatment approach

A

WHO analgesic ladder (step up if pain persisting or increasing)
step down if pain is resolving

21
Q

what is step 1

A

Non-opioid
+/- adjuvant
analgesic

22
Q

what is step 2

A

Opioid for mild-
moderate pain
+ Non-opioid
+/- adjuvant
analgesic

23
Q

what is step 3

A

Opioid for
moderate-severe
pain
+ Non-opioid
+/- adjuvant
analgesic

24
Q

Select the non-opioids
A. acetaminophen
B.gabapentinoids
C. topical agents
D. NSAIDS

25
what are the available formulations of acetaminophen
Capsule  Chewable tablet (80mg or 160mg)  Liquid/gel  IV solution
26
What are clinical pearls of NSAIDS
take with food  Caution use in geriatric patients due to increased side effects (Beer’s list) Avoid systemic NSAIDs in patients with cardiac history (can use topical NSAIDs)  Avoid in severe liver disease or chronic kidney disease
27
what are the available formulations of NSAIDS (aspirin)
Chewable tablet  Tablet  EC tablet  Capsule  ER capsule  Suppository
28
what is the dosing of NSAIDS (aspirin)
Adults: 25mg-1000mg PO q4-6h PRN (max 4g/day) Pediatrics: Avoid (Reye’s syndrome)
29
What is the recommended dosing for ibuprofen (Advil, Motrin) in peds?
5-10 mg/kg PO Q4-6H PRN (max 40mg/kg/day or 2400mg, whichever is less
30
What is the recommended dosing for diclofenac
Adults: 50mg PO q8h or 2-4 g applied topically 4 times/day
31
what are the clinical pearls of diclofenac
Minimal systemic side effects with topical gel  Some formulations available OTC
32
What is the dosing of Naproxen (aleve,Naprosyn)
Recommended dosing  Adults: 220-500mg PO q6-12h (max 1000mg/day)  Some formulations available OTC
33
What is ketorolac dosing
Adults: 15-30mg IV/IV q6h prn or 10mg PO q6h prn Pediatrics: 0.5mg/kg/dose IM/IV q6h prn
34
What is ketorolac formulations
Tablet  IV/IM solution  Nasal spray  Ophthalmic solution
35
What are the available formulations of Celecoxib
Capsule  Oral solution (less common)
36
what are the dosing of celecoxib
Adults: 200mg PO BID