Non Disjunction Flashcards
1
Q
What is nondisjunction
A
Occurs when homologous chromosomes dokt seperate during anaphase 1 or sister chromatids do not seperate during anaphase 2. Can end up with too much or too little genetic info
2
Q
Trisomy
A
A zygote contains 47 chrimosomes. Eg Klinefelter syndrome = xxy
3
Q
Monosomy
A
Zygote contains 45 chromosomes . Eg turner syndrome- female only has one X chromosome
4
Q
Karyotype
A
Picture of chromosomes arranged in homologous pairs in descending order by size, with sex chromosome placed last. ( nondisjunctioning can be identified through karyotyping )
5
Q
Prenatal testing
A
Used to detect small- scale mutations of chromosomal alterations in a fetus
6
Q
Amniocentesis
A
Cells in the amniotic fluid are tested. Chorionic villus sampling: chorionic villi are tested
