NMBD Reversal

Question 1

What is neostigmine?

Answer 1

Acetylcholinasterase inhibitor

Question 2

Neostigmine dose

Answer 2

40 to 70 mcg/kg (0.04-0.07 mg/kg)

Question 3

Max dose of neostigmine

Answer 3

80 mcg/kg

Question 4

What should be given with neostigmine?

Answer 4

Glycopyrrolate: 0.2mg for every 1mg neostigmine

Glyco will counteract the excessive choliergic effects of neostigmine

Question 5

Is glycopyrrolate given before, in conjunction with, or after neostigmine administration?

Answer 5

Glycopyrrolate is given before neostigmine reversal.

Question 6

Max Dose of glycopyrrolate?

Answer 6

1mg

Question 7

Edrophonium dose

Answer 7

1 to 1.5 mg/kg
Just know 1 mg… per Castillo

Question 8

Atropine

Answer 8

7 to 10 mcg/kg
Matches profile of Edrophonium

Question 9

Glycopyrrolate (dose from Castillo)

Answer 9

7 to 15 mcg/kg (1 mg max)
Matches profile to both Neostigmine and Pyridostigmine

Question 10

Sugammadex dose for…
Moderate Block:
Deep Block:
Extreme Block:

Answer 10

Moderate - 2 mg/kg
Deep - 4 mg/kg
Extreme - 8-16 mg/kg