Nitrofuranos Flashcards

1
Q

Antibiótico?

A

NITROFURANTOINA

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2
Q

Bactericida o bacteriostatico?

A

Bactericida

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3
Q

Mecanismo de acción ?

A

Degradan al ADN e Inhibe la síntesis proteica

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4
Q

Vía de administración

A

Vía oral

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5
Q

Vía de excreción

A

Renal

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6
Q

Cobertura ?

A

Pseudomonas

Bacilos aerobios

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7
Q

Efectos adversos ?

A

Neuropatia periférica
Fibrosis pulmonar
Anemia hemolitica (3er trimestre)
Parálisis del facial

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8
Q

Embarazo?

A

Si

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9
Q

BHE

A

No

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10
Q

Indicaciones ?

A

IVU no complicadas

PROFILAXIS para IVU en mujeres

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11
Q

Contraindicaciones

A

Embarazadas entre la semana 38 y 42
Periparto ( no usar de 1 a 2 semanas antes del parto para evitar hemolisis)
IVU causada por Proteus ( el pH alcalino inactiva la NITROFURANTOINA)
Neonatos
Pacientes con déficit de G6PD

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12
Q

Alcanza buenas concentraciones sistémicas ?

A

No

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