Azoles Flashcards

1
Q

Mecanismo de acción

A

Inhiben la síntesis de ergosterol uniéndose a la 14 alfa demetilasa

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2
Q

Antifúngicos

A

Fluconazol

Itraconazol

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3
Q

Vía de admin

A

Fluconazol: vía oral y endovenosa

Itraconazol : vía oral

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4
Q

Vía de excreción

A

Fluconazol : renal

Itraconazol: hepatica

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5
Q

Vía de excreción

A

Fluconazol : renal

Itraconazol : hepatica y renal

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6
Q

Dismórficos

A
Histoplasma 
Blastomyces
Coccidioides
Paracoccidioides 
Sporotrix schenkii
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7
Q

Efectos adversos del fluconazol

A

Nauseas
Vomitos
Cefalea
Arritmias

Todos los azules causan hipocalemia e hipocalcemia

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8
Q

Efectos adversos del itraconazol

A

Inhibición del CY450

Cefalea

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