Cefalosporinas De Segunda Generacion Flashcards

1
Q

CuLes son las cefalosporinas de segunda generacion ?

A

Cefuroxima
Cefaclor
Cefoxitina
Cefotetan

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2
Q

Vías de administración

A

Cefuroxima VO Y EV
cefaclor VO
Cefoxitin: EV
Cefotetan: EV E IM

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3
Q

Vía de excreción

A

Renal

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4
Q

Cobertura;

A

Cocos +
estrepto y staph
Cocos -
moraxella catarrhalis, N. Gonorrhoeae (gonococo)
Bacilos -
Shigella, e. Coli, H. influenzae, H pylori, proteus, salmonella Y Vibrio Cholerae

Anaerobios:
Cefuroxima + metronidazol
Cefoxitin y cefotetan: bacteroides fragilis
CEFACLOR NO CUBRE ANAERÓBICOS

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5
Q

Efectos adversos

A

Hipersensibilidad con penicilina de 10-15%

Complicaciones por anaerobios en cefoxitin a y cefotetan

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6
Q

Embarazo

A

Si

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7
Q

BHE

A

Cefuroxima si

Los otros no

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8
Q

Indicaciones de cefuroxima

A
IVU
 IPTB
IVRA
Osteomielitis (seguimiento)
Meningitis
NAC de 2da línea 
Peritonitis secundaria + metronidazol
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9
Q

Indicaciones de CEFACLOR

A

IVU
IPTB IVRA
Osteomielitis (seguimiento

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10
Q

Indicaciones de cefoxitina y cefotetan

A

Infecciones de la boca
IPTB
Peritonitis secundaria
EPI en embarazadas (+ azitro Clamydia)

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11
Q

Contraindicaciones de CRFACLOR

A

Neumonía

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12
Q

Alcanza menos concentraciones en SNC y pulmón que las cefalosporinas de 3ra generacion

A

Cefuroxima

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