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Pharm Y3S2 > NICE Guidelines for Pharmacological Treatment > Flashcards

NICE Guidelines for Pharmacological Treatment Flashcards

1
Q

First line in schizophrenia.

A

Atypical antipsychotics

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2
Q

Second line in schizophrenia

A

Typical antipsychotics

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3
Q

For treatment resistant schizophrenia.

A

Clozapine

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4
Q

First line in bipolar mania.

A

Trial antipsychotic such as olanzapine

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5
Q

First line in bipolar depression.

A

Olanzapine with or without fluoxetine

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6
Q

First line in bipolar maintenance.

A

Lithium

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7
Q

Second line in bipolar maintenance.

A

Sodium valproate

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8
Q

Last line in bipolar depression.

A

Lamotrigine

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9
Q

First line in early Parkinson’s.

A

L-dopa and DDi

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10
Q

Second line in early Parkinson’s.

A

Dopamine agonist

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11
Q

Option in advanced Parkinson’s with optimal oral treatment.

A

SC apomorphine

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12
Q

First line in tremor with Parkinson’s.

A

Anticholinergics

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13
Q

Add in for Parkinson’s with dyskinesia or motor fluctuation.

A

COMT inhibitor

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14
Q

Preferred in mild Parkinson’s or late stage add in.

A

MAO-B inhibitor

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15
Q

Add in for dyskinesias in late stage Parkinson’s.

A

Amantadine

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16
Q

First line in cognitive symptoms of dementia.

A

AChE inhibitor

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17
Q

First line alternative in dementia.

A

Memantine

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18
Q

Licensed antipsychotic for BPSD.

A

Risperidone

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19
Q

First line in GAD.

A

SSRI

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20
Q

Second line in GAD.

A

Alternative SSRI or SNRI

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21
Q

Third line in GAD.

A

Pregabalin

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22
Q

First line in panic disorder.

A

SSRI

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23
Q

Second line in panic disorder.

A

Imipramine

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24
Q

First line in social anxiety disorder.

A

SSRI

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25
Q

Second line in social anxiety disorder.

A

Alternative SSRI or SNRI

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26
Q

Third line in social anxiety disorder.

A

MAOI

27
Q

Licensed for short term use in GAD crisis.

A

Diazepam

28
Q

Licensed for physical anxiety symptoms.

A

Propranolol

29
Q

First line in sulphonylurea overdose.

A

IV dextrose

30
Q

First line in beta-blocker overdose.

A

Fluid and atropine

31
Q

Second line in beta-blocker overdose.

A

IV glucagon infusion over 5-10 minutes

32
Q

First line in CCB overdose.

A

Fluid resus followed by calcium salts

33
Q

Second line in CCB overdose.

A

High dose insulin-dextrose infusion

34
Q

First line in toxic alcohol overdose.

A

Ethanol (preferred substrate)

35
Q

Second line in toxic alcohol overdose.

A

Fomepizole

36
Q

Adjunct in cyanide poisoning.

A

Sodium thiosulphate

37
Q

Treatment in severe cyanide poisoning.

A

Dicobalt edetate

38
Q

Unlicensed treatment for cyanide poisoning.

A

Hydroxycobalamin

39
Q

First line in pre-hospital first aid of cyanide poisoning.

A

Amylnitrite

40
Q

First line cyanide poisoning. IMMEDIATE

A

Oxygen to reverse metabolic acidosis

41
Q

First line in BZD only overdose.

A

Flumazenil

42
Q

First line in opioid overdose.

A

Naloxone

43
Q

First line in paracetamol overdose.

A

N-acetylcysteine

44
Q

Indication for charcoal haemoperfusion.

A

Theophylline or carbamazepine overdose

45
Q

Indication for urinary alkalisation.

A

Overdose of aspirin

46
Q

First line BZD in status epilepticus.

A

IV lorazepam

47
Q

Buccal BZD alternative in status epilepticus.

A

Midazolam

48
Q

Rectal BZD alternative in status epilepticus.

A

Diazepam

49
Q

First line AED in status epilepticus.

A

Phenytoin

50
Q

Last line in status epilepticus.

A

Induction of coma

51
Q

First line in partial seizures.

A

Carbamazepine

52
Q

Second line in partial seizures.

A

Sodium valproate

Lamotrigine

53
Q

First line in generalised tonic-clonic seizures.

A

Sodium valproate

Lamotrigine

54
Q

Second line in generalised tonic-clonic seizures.

A

Carbamazepine

Topiramate

55
Q

First line in absence seizures.

A

Sodium valproate

56
Q

Second line in absence seizures.

A

Lamotrigine

Ethosuximide

57
Q

Contraindicated in MAT seizures.

A

Carbamazepine

58
Q

First line in epilepsy in pregnancy.

A

Lamotrigine

59
Q

First line in Dravets syndrome.

A

Sodium valproate

60
Q

Second line in Dravets syndrome.

A

Sodium valproate

And clobozam

61
Q

Third line in Dravets syndrome.

A

Sodium valproate
And clobozam
And stiripentol

62
Q

First line in Lennox-Gastaut syndrome.

A

Sodium valproate

63
Q

Second line in Lennox-Gastaut syndrome.

A

Lamotrigine
Clobozam
Topiramate
Phenytoin

Pharm Y3S2 (29 decks)

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