Drug Actions Flashcards by Maeve Sparks

What is the drug class and action of olanzapine?

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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What is the drug class and action of risperidone?

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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What is the drug class and action of zuclopenthixol?

Typical antipsychotic

Post-synaptic dopamine receptor blocker

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What is the drug class and action of clozapine?

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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What is the drug class and action of aripiprazole?

Partial agonist at D2 receptors, reducing but not blocking activity

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What is the drug class and action of quetiapine?

Atypical antipsychotic

Post-synaptic dopamine-serotonin receptor blocker

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What is the drug class and action of haloperidol?

Typical antipsychotic

Post-synaptic dopamine receptor blocker

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What is the drug class and action of chlorpromazine?

Typical antipsychotic

Dopamine D2 receptor inhibitor

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What is the drug class and action of donepezil?

AChE inhibitor

Increase amount of acetylcholine present in the synapse

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What is the drug class and action of rivastigmine?

AChE inhibitor

Increase amount of acetylcholine present in the synapse

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What is the drug class and action of ropinirole?

Non-ergot dopamine agonist

Agonists at post-synaptic dopamine receptors

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What is the drug class and action of pramipexole?

Non-ergot dopamine agonist

Agonists at post-synaptic dopamine receptors

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What is the drug class and action of levodopa?

Dopamine precursor

Increasing dopamine available in presynaptic neurones

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What is the drug class and action of entacapone?

COMT inhibitor

Prevents metabolism of levodopa to 3-O-methyldopa

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What is the drug class and action of pergolide?

Ergot dopamine agonist

Agonist at post-synaptic dopamine receptors

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What is the drug class and action of rasagiline?

MAO-B inhibitor

Prevent metabolism of dopamine, increasing dopamine available at receptors

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What is the drug class and action of carbidopa?

DD inhibitor

Prevent peripheral metabolism of levodopa

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What is the drug class and action of sertraline?

SSRI

Boost serotonin by blocking reuptake

What is the drug class and action of citalopram?

SSRI

Boost serotonin by blocking reuptake

What is the drug class and action of fluoxetine?

SSRI

Boost serotonin by blocking reuptake

What is the drug class and action of mirtazapine?

NaSSA

Antagonist of adrenergic, 5-HT2A, 5-HT2C and H1 receptors

What is the drug class and action of venlafaxine?

SNRI

Boost serotonin and noradrenaline by blocking reuptake

What is the drug class and action of amitriptyline?

TCA

Boost serotonin and noradrenaline by blocking reuptake

What is the drug class and action of isocarboxazid?

MAOI

Stop breakdown of serotonin and noradrenaline

What is the drug class and action of phenelzine?

MAOI | Stop breakdown of serotonin and noradrenaline

What is the drug class and action of duloxetine?

SNRI | Boost serotonin and noradrenaline by blocking reuptake

What is the drug class and action of dosulepin?

TCA | Boost serotonin and noradrenaline by blocking reuptake

What is the drug class and action of amisulpride?

Typical antipsychotic | Dopamine D2 receptor inhibitor

What is the drug class pregabalin?

Anti-epileptic

What is the drug class and action of aspirin?

NSAID | Irreversible inhibitor of COX-1 and COX-2, Prostaglandin production reduced

What is the drug class and action of ibuprofen?

NSAID | Reversible inhibitor of COX-1 and COX-2, Prostaglandin production reduced

What is the drug class and action of paracetamol?

Antipyretic | Paracetamol inhibits COX-3 and (weakly) COX-2, Prostaglandin production reduced

What is the drug class and action of morphine?

Opioid | Agonist at opioid receptor, preventing GABA, thus allowing descending pathway to work with MOP

What is the drug class and action of ondansetron?

5-HT3 antagonist | Inhibits serotonin in CTZ and GI tract

What is the drug class and action of aprepitant?

NK1 antagonist | Inhibits substance P in CTZ

What is the drug class and action of metoclopramide?

D2 antagonist | Inhibits dopamine in the CTZ

What is the drug class and action of domperidone?

D2 antagonists | Inhibits dopamine in the CTZ

What is the drug class and action of hyoscine?

Anticholinergic | Inhibits ACh primarly present in vestibular centre and GI tract

What is the drug class and action of cyclizine?

Anticholinergic | Inhibits ACh primarly present in vestibular centre and GI tract

What is the drug class and action of promethazine?

``` Antihistamine Inhibits histamine (primarly) present in vestibular centre and GI tract ```

What is the drug class and action of zopiclone?

Z drug | Stimulates hyperpolarisation of postsynaptic neurone via GABAa receptors

What is the drug class and action of diazepam?

BZD | Stimulates hyperpolarisation of postsynaptic neurone via GABAa receptors

What is the drug class and action of memantine?

NMDA receptor antagonist | Dampens glutamate firing thus having a neuroprotective factor

What is the drug class and action of thiopental?

Barbiturate | Stimulates hyperpolarisation of postsynaptic neurone via GABAa receptors