New topics

Question 1

too much Fe is?

Answer 1

hemochromatosis

Question 2

hemochromatosis heredity is?

Answer 2

Auto res

Question 3

Skin hyperpigment, diabetes, ED could be?

Answer 3

hemochromatosis

Question 4

hemochromatosis diag?

Answer 4

High FE, Ferritin sat. genetic testing

Question 5

hemochromatosis tx?

Answer 5

phleb

Question 6

hemochromatosis is associated with

Answer 6

cirrhosis, HCC, BRONZE diabetes, cardiomyopathy

Question 7

Neutropenia is due to?

Answer 7

Phenothiazines, or chemo.

Question 8

is HIV associated with Lymphocytopenia?

Answer 8

Yes

Question 9

Multiple Myeloma can be casued by? its a dysplasti hematopoetic progenitor cell

Answer 9

Myelodysplasia

Question 10

Myelodysplasia diag?

Answer 10

CBC, peripheral smear, biopsy

Question 11

Myelodysplasia tx?

Answer 11

Transfusion, SCT (curative)

Question 12

increased hgb, hct is?

Answer 12

Polycythemia

Question 13

primery Polycythemia

Answer 13

myeloid cell proliferation

Question 14

2nd Polycythemia

Answer 14

high alt

Question 15

Jak2, shower pruritis, PLETHERA, visual changes (amarosus fugax), splenomegaly

Answer 15

Polycythemia

Question 16

Polycythemia diag?

Answer 16

CBC, erythropoeitin

Question 17

Polycythemia tx?

Answer 17

Phlebotomy (45% hct) ->splenectomy.

Question 18

Polycythemia complications?

Answer 18

Thrombus, Budd chiari, acute myeloid leukemia

Question 19

What is BUDD CHIARI?

Answer 19

Hepatic vein thrombus - splenomegaly and ascites due to fluid backup. + varices (anal, esophageal, caput medusa).

Question 20

Mild allergi hypersensitivity rxn or febrile non-hemolytic.

Answer 20

Transfusion reaction

Question 21

Acute rxn of Transfusion reaction is?

Answer 21

Taco = too much fluid
Trali = immune rxn, pum edema

Question 22

delayed rxn of Transfusion reaction is?

Answer 22

anamestic responce = immune responce

Question 23

Transfer rxn tx?

Answer 23

stop transfusion
hemolysis - aggressive IV
Anaphylactic - epi, antihistamine.

Question 24

intrinsic pathway factors are?

Answer 24

12,11,9,8- slow

Question 25

Extrinsic pathway is?

Answer 25

7,5,10, thrombin, fibrin

Question 26

Heparin antidote is?

Answer 26

Protamine sulfate

Question 27

LMWH - -parin (xa) can cause? antidote?

Answer 27

renal failure | Protamine sulfate

Question 28

warfarin. 1972 chevy silverado?

Answer 28

Vitamin K dependant | 10, 9, 7, 2 Protein C and S

Question 29

Warfarin can cause what problem?

Answer 29

Skin Necrosis

Question 30

Direct thrombin inhibiters are?

Answer 30

dabigatron, argatroban

Question 31

Direct thrombin inhibiters antidote is?

Answer 31

Idarucizumab - (direct dare)

Question 32

Xa inhibiters -xabans CI?

Answer 32

pregnancy, bleeding.

Question 33

Xa inhibiter antidote is?

Answer 33

AndeXanet

Question 34

if you have a DVT or PE what is the tx?

Answer 34

Fondaparinux

Question 35

ASA CI?

Answer 35

tinnitis + toxicity | and Reyes, Pregnancy, Metabolic acidosis

Question 36

ADP inhibitor is?

Answer 36

Clopidegral

Question 37

Clopidegral is used in?

Answer 37

NSTEMIs and unstable angina

Question 38

Clopidegral CI?

Answer 38

TTP

Question 39

tPA - plase + Urokinase used up to 4.5 hours of strokes CI is?

Answer 39

intracranial hemorrhage, AV malfomation, uncontrolled HTN, Neurosurg trauma (3 months)