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hematology > New topics > Flashcards

New topics Flashcards

1
Q

too much Fe is?

A

hemochromatosis

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2
Q

hemochromatosis heredity is?

A

Auto res

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3
Q

Skin hyperpigment, diabetes, ED could be?

A

hemochromatosis

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4
Q

hemochromatosis diag?

A

High FE, Ferritin sat. genetic testing

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5
Q

hemochromatosis tx?

A

phleb

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6
Q

hemochromatosis is associated with

A

cirrhosis, HCC, BRONZE diabetes, cardiomyopathy

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7
Q

Neutropenia is due to?

A

Phenothiazines, or chemo.

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8
Q

is HIV associated with Lymphocytopenia?

A

Yes

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9
Q

Multiple Myeloma can be casued by? its a dysplasti hematopoetic progenitor cell

A

Myelodysplasia

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10
Q

Myelodysplasia diag?

A

CBC, peripheral smear, biopsy

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11
Q

Myelodysplasia tx?

A

Transfusion, SCT (curative)

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12
Q

increased hgb, hct is?

A

Polycythemia

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13
Q

primery Polycythemia

A

myeloid cell proliferation

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14
Q

2nd Polycythemia

A

high alt

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15
Q

Jak2, shower pruritis, PLETHERA, visual changes (amarosus fugax), splenomegaly

A

Polycythemia

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16
Q

Polycythemia diag?

A

CBC, erythropoeitin

17
Q

Polycythemia tx?

A

Phlebotomy (45% hct) ->splenectomy.

18
Q

Polycythemia complications?

A

Thrombus, Budd chiari, acute myeloid leukemia

19
Q

What is BUDD CHIARI?

A

Hepatic vein thrombus - splenomegaly and ascites due to fluid backup. + varices (anal, esophageal, caput medusa).

20
Q

Mild allergi hypersensitivity rxn or febrile non-hemolytic.

A

Transfusion reaction

21
Q

Acute rxn of Transfusion reaction is?

A 
Taco = too much fluid
Trali = immune rxn, pum edema
22
Q

delayed rxn of Transfusion reaction is?

A

anamestic responce = immune responce

23
Q

Transfer rxn tx?

A

stop transfusion
hemolysis - aggressive IV
Anaphylactic - epi, antihistamine.

24
Q

intrinsic pathway factors are?

A

12,11,9,8- slow

25
Q

Extrinsic pathway is?

A

7,5,10, thrombin, fibrin

26
Q

Heparin antidote is?

A

Protamine sulfate

27
Q

LMWH - -parin (xa) can cause? antidote?

A

renal failure

Protamine sulfate

28
Q

warfarin. 1972 chevy silverado?

A

Vitamin K dependant

10, 9, 7, 2 Protein C and S

29
Q

Warfarin can cause what problem?

A

Skin Necrosis

30
Q

Direct thrombin inhibiters are?

A

dabigatron, argatroban

31
Q

Direct thrombin inhibiters antidote is?

A

Idarucizumab - (direct dare)

32
Q

Xa inhibiters -xabans CI?

A

pregnancy, bleeding.

33
Q

Xa inhibiter antidote is?

A

AndeXanet

34
Q

if you have a DVT or PE what is the tx?

A

Fondaparinux

35
Q

ASA CI?

A

tinnitis + toxicity

and Reyes, Pregnancy, Metabolic acidosis

36
Q

ADP inhibitor is?

A

Clopidegral

37
Q

Clopidegral is used in?

A

NSTEMIs and unstable angina

38
Q

Clopidegral CI?

A

TTP

39
Q

tPA - plase + Urokinase
used up to 4.5 hours of strokes
CI is?

A

intracranial hemorrhage, AV malfomation, uncontrolled HTN, Neurosurg trauma (3 months)

hematology (6 decks)

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