Hem Cancer

Question 1

Leukemias are what 2 cell lines?

Answer 1

Myeloid or Leukoyte

Question 2

kids with leukimia is?

Answer 2

ALL

Question 3

MC sxs in ALL is?

Answer 3

Fever - assocaited with downs (alzheimers)

Question 4

ALL sxs in addition to pancytopenia

Answer 4

fever, crowd out bone marrow. lots of blasts.

Question 5

ALL tx?

Answer 5

Hydroxyurea (like Sickle cell)

chemo, MTX

Question 6

Auer rods is always AML,

AML sxs?

Answer 6

infections, ginvigal bleeding, >100,000 WBC

Question 7

AML tx?

Answer 7

Combo chemo - Blasts with chemo

Question 8

Tumor lysis syndrome is?

Answer 8

Large number of cancer cell in circulation after Combo chemo - IVF, allopurinol

Question 9

Is CLL more common? (RAI staging)

Answer 9

Yes

Question 10

Splenomegaly is associated with?

Answer 10

CML

Question 11

Smudge cells are with?

Answer 11

CLL

Question 12

CLL tx is?

Answer 12

Fludarabine

Question 13

CML sxs?

Answer 13

anemia, fatigue, vague - wt lose. recurrant infections.

Question 14

Philidelphia chrome is

Answer 14

CML, >150,000

Question 15

BCR -ABL gene is?

Answer 15

CML

Question 16

reed sternberg cell, Bimodal 20s and 50s

Answer 16

hogdkins lymphoma - Owl eyes

Question 17

Painless supraclavicular LAD, pain in lymphnodes with EtOH

Answer 17

hogdkins lymphoma

Question 18

B sxs?

Answer 18

Fever, wt loss, anorexia, night sweats - Ann Arbor system.

Question 19

Gingival hyperplasia is?

Answer 19

hogdkins lymphoma

Question 20

hogdkins lymphoma tx?

Answer 20

ABVD - Adrian, Bleo, Vinblast, Dacarba

Question 21

55 male with painless LAD

Answer 21

Non-hodgkins Lymphoma + B sxs

Question 22

LDH is a marker of

Answer 22

cancer cells

Question 23

Non-hodgkins Lymphoma tx?

Answer 23

Chemo and bone marrow transplant.

Question 24

Malt lymphoma and Burkitts is associated with?

Answer 24

Non-hodgkins Lymphoma

Question 25

EBV in Non-hodgkins Lymphoma leads to

Answer 25

Burkitts

Question 26

plasma cell cancer is?

Answer 26

Multiple Myeloma - increased IgA and IgG

Question 27

Xray with punched out lesions is

Answer 27

Multiple Myeloma

Question 28

CRABI is?

Answer 28

Renal faliure, infections, anemia, bone paine,

Question 29

Multiple Myeloma diag?

Answer 29

HyperCal, Rouleaux, Bence jones, M spike, SPEP spike.

Question 30

Multiple Myeloma tx?

Answer 30

SCT, thalidomide, ICS, Bisphosphonate