Hem Cancer Flashcards

1
Q

Leukemias are what 2 cell lines?

A

Myeloid or Leukoyte

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2
Q

kids with leukimia is?

A

ALL

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3
Q

MC sxs in ALL is?

A

Fever - assocaited with downs (alzheimers)

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4
Q

ALL sxs in addition to pancytopenia

A

fever, crowd out bone marrow. lots of blasts.

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5
Q

ALL tx?

A

Hydroxyurea (like Sickle cell)

chemo, MTX

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6
Q

Auer rods is always AML,

AML sxs?

A

infections, ginvigal bleeding, >100,000 WBC

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7
Q

AML tx?

A

Combo chemo - Blasts with chemo

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8
Q

Tumor lysis syndrome is?

A

Large number of cancer cell in circulation after Combo chemo - IVF, allopurinol

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9
Q

Is CLL more common? (RAI staging)

A

Yes

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10
Q

Splenomegaly is associated with?

A

CML

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11
Q

Smudge cells are with?

A

CLL

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12
Q

CLL tx is?

A

Fludarabine

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13
Q

CML sxs?

A

anemia, fatigue, vague - wt lose. recurrant infections.

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14
Q

Philidelphia chrome is

A

CML, >150,000

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15
Q

BCR -ABL gene is?

A

CML

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16
Q

reed sternberg cell, Bimodal 20s and 50s

A

hogdkins lymphoma - Owl eyes

17
Q

Painless supraclavicular LAD, pain in lymphnodes with EtOH

A

hogdkins lymphoma

18
Q

B sxs?

A

Fever, wt loss, anorexia, night sweats - Ann Arbor system.

19
Q

Gingival hyperplasia is?

A

hogdkins lymphoma

20
Q

hogdkins lymphoma tx?

A

ABVD - Adrian, Bleo, Vinblast, Dacarba

21
Q

55 male with painless LAD

A

Non-hodgkins Lymphoma + B sxs

22
Q

LDH is a marker of

A

cancer cells

23
Q

Non-hodgkins Lymphoma tx?

A

Chemo and bone marrow transplant.

24
Q

Malt lymphoma and Burkitts is associated with?

A

Non-hodgkins Lymphoma

25
Q

EBV in Non-hodgkins Lymphoma leads to

A

Burkitts

26
Q

plasma cell cancer is?

A

Multiple Myeloma - increased IgA and IgG

27
Q

Xray with punched out lesions is

A

Multiple Myeloma

28
Q

CRABI is?

A

Renal faliure, infections, anemia, bone paine,

29
Q

Multiple Myeloma diag?

A

HyperCal, Rouleaux, Bence jones, M spike, SPEP spike.

30
Q

Multiple Myeloma tx?

A

SCT, thalidomide, ICS, Bisphosphonate