New therapeutic strategies against HIV

Question 1

What are microbicides?

Answer 1

A substance that can reduce the transmission of HIV and other STI pathogens when applied vaginally and, possibly, rectally.

Question 2

What is the influence of factors in breast milk (BSSL) and seminal plasma (mucin6) on HIV-1?

Answer 2

Factors in breast milk (BSSL) and seminal plasma (mucin6) can interfere with HIV1 capture by DCs. This may explain low transmission rates.