Neutrophilz And Macrophagez

Question 1

Mature cells that can attack and destroy bacteria even in circulating blood

Answer 1

Neutrophils

Question 2

Monocytes that enter tissue and begin to swell as much as five fold

Answer 2

Macrophages

Question 3

WBCs enter tissue spaces by _______ and move through tissue by _______

Answer 3

Diapedesis; ameboid motion

Question 4

_______ usually phagocytize 3-20 bacteria the dies, while _____ 100 bacteria an can survive for many more months

Answer 4

Neutrophil, macrophage

Question 5

Lysosomes form macrophages contin large amounts of ______ that digest thick lipid bacterial membrane (tb)

Answer 5

Lipase

Question 6

Phagocytes also have _______ that contain bacterial ixidizing agents included large quantities of superoxide (O2-), hydrogen peroxide (H2O2) and hydroxyl ions (OH-) lethal to bacteria

Answer 6

Peroxisomes

Question 7

lysosomal enzyme that catalyze the reaction between H2O2 and Cl- that form _______ which is bactericidal

Answer 7

Myeloperoxidase; hypochlorite

Question 8

Combi of monocytes, few specialized endothelial cell in bone marrow, spleen and lymph nodes

Answer 8

Reticuloendothelial system

Question 9

Complex tissue chsnge when tissue injury occurs, substances are release and cause dramstic secondary change in surrounding uninjured

Answer 9

Inflammation

Question 10

first results of inflammation _____ the area of injury from remaining tissue and these tissue spaces are blocked by _____ so fluid barely flows and this delay the spread of bacteria

Answer 10

Wall-off; fibrinogen clots

Question 11

Is the first line of defense against infection that occurs within minutes and _______ break loose and become mobile forming 1st line of defense

Answer 11

Tissue macrophages; sessile macrophages

Question 12

Large number of neutrophils begin to invade inflamed area from blood providing ________ of defense. This invasion is caused by _______ secreted by ______ macrophages

Answer 12

2nd line of defense; cytokines; acitvated

Question 13

Is the second marcophage invasion by monocytes from blood that enter inflamed tissue and enlarge

Answer 13

3rd line of defense

Question 14

Increase production of granulocytes and monocytes by bone marrow

Answer 14

4th line of defense

Question 15

Is the weak phagocytes and exhibit chemotaxis, often produced in large numbers with parasitic infections as they attach themselves to parasites and release substance to kill it

Answer 15

Eosinophils

Question 16

Eosinophils kills bacteria by:

1. Releasing ______ from their granules
2. Releasing _______ of oxygem
3. Releasing _____ called major basic protein

Answer 16

Hydrolytic enzyme;
High reactive form;
Larvacidal polypeptide

Question 17

Mast cells and basophils release ______ that causes esinophil to mugrate toward inflamed area

Answer 17

Eosinophil chemotactic factor (ECF)

Question 18

Bone marrow produces very few RBCs causes include irradiation, drugs and chemicals

Answer 18

Leukopenia

Question 19

Malignant progressive disease, bone marrow and other blood forming organs produce increased number of immature / abnormal leukocytes

Answer 19

Leukemia