Neutropenic Sepsis

Question 1

Red flags for neutropenic sepsis

Answer 1

Unwell, pyrexial sepsis
Chemotherapy in last 6wks
BMF syndrome (myelodysplasia)
Functional neutropenia e.g. new dx of haematological malignancy
On immunosuppressive agents

Question 2

Treatment of neutropenic sepsis

Answer 2

ABCDE
Bloods - FBC, U&E, LFT, CRP, clotting screen
ABG - lactate
Cultures - before abx started
Viral PCR, atypical serology
Tazocin and amikacin IV, fluid resus, other Ix once stable e.g. CXR