Neurotransmitters and their receptors Flashcards

1
Q

In general neurotransmitters and their recpetors can be what 2 types?

A

small molecules

neuropeptides

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2
Q

Where does ACh fit in as a neurotransmitter?

A
in a class all by itself 
even though it was the first neurotransmitter to be isolated
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3
Q

What does ACh do at the NMJ?

A

it has excitatory effects

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4
Q
Biogenic amines (modified amino acids): 
from tyrosine?
A

norepinephrine aka noradrenline
and
epinephrine aka adrenline and dopamine

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5
Q
Biogenic amines (modified amino acids): 
from tryptophan
A

seratonin

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6
Q
Biogenic amines (modified amino acids): 
from histadine
A

histamine

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7
Q

How do neuropeptides (peptides) act as neuromodulators?

A

by inhibiting the release of substance P

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8
Q

What is higher than normal in patients with fibromyalgia?

A

substance P

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9
Q

What is substance P?

A

relays pain signals

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10
Q

What happens if substance P release is inhibited?

A

pain is not perceived

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11
Q

NO and CO (gasses) are novel messengers that stimulate the synthesis of?

A

the second messenger cGMP (cyclic guanosine monophosphate)

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12
Q

amino acid
biogenic amines (modified amino acids)
neuropeptides
novel messengers

A

4 main types of neurotransmitters

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13
Q

glutamate
aspartate
GABA (gamma-amino butyric acid)
glycine

A

amino acids

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14
Q

norepinephrine aka noradrenaline
epinephrine aka adrenaline and dopamine
seratonin
histamine

A

biogenic amines

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15
Q

enkephalins
endomorphins
dynomorphins
endorphins

A

4 neuropeptides (peptides) that are natural opiates that block the perception of pain

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16
Q

ATP
nitric oxide- NO
carbon monoxide- CO

A

novel messengers